HER2 ātras internalizācijas un novirzītas cilvēku tirdzniecības molekulārais

HER2 ātras internalizācijas un novirzītas cilvēku tirdzniecības molekulārais mehānisms, ko izraisa anti-HER2 biparatopiskais antiviela

  • HER2 (cilvēka epidermas attīstības problēmas 2. receptora), ErbB2 receptoru tirozīna kināzes, pastiprināšanās un pārmērīga ekspresija ir saistīta ar lielāko daļu cilvēku vēža un metastāžu. Ir ziņots, ka bispecifiska četrvērtīga anti-HER2 antiviela (anti-HER2-Bs), kas koncentrējas uz diviem HER2 nepilējošiem epitopiem IV zonā (trastuzumabs) un II zonā (39S), izraisa ātru HER2 internalizāciju un videi draudzīgu degradāciju. receptori. 
  • Šajā pētījumā mēs izpētījām šīs antivielu izraisītās ātrās HER2 internalizācijas un intracelulārās tirdzniecības molekulāro mehānismu. Izmantojot kvantitatīvo fluorescējošo attēlveidošanu, mēs pretstatām anti-HER2-B un tā vecāku roku antivielu internalizācijas kinētikai atsevišķi vai maisījumos un daudzos internalizāciju veicinošos apstākļos. Rezultāti parādīja, ka ātrai anti-HER2-B internalizācijai izšķiroša nozīme bija vienlaicīgai katra epitopa iesaistei.
  • Anti-HER2-B un vecāku roku antivielu mobilā uzņemšana notika no klatrīna atkarīgas endocitozes veidā; tomēr antivielas šūnās satur pilnīgi atšķirīgus cilvēku tirdzniecības ceļus. Trastuzumabs 2 stundu laikā disociējās no HER2, ļaujot receptoriem atkārtoti pārstrādāt, savukārt anti-HER2-B palika saistīti ar receptoru visā endocītiskajā ceļā, pārdodot receptoru ubikvitināciju, tirdzniecību ar lizosomām un videi draudzīgu noārdīšanos.
  • Atbilstoši HER2 novirzīšanai uz degradāciju, anti-HER2-B ievērojami samazināja HER2 izdalīšanos un mainīja tā eksosomālo eksportu. Kopā šie rezultāti ļauj labāk izprast anti-Her2-B kustības mehānismu un var sniegt informāciju par racionālu anti-HER2 terapijas dizainu papildus dažādām bispecifiskām molekulām.

Cilvēkiem ar receptoru saistošās domēna specifiskās neitralizējošās monoklonālās antivielas pretstatā SARS-CoV un SARS-CoV-2

Ārkārtējā akūtā elpošanas sindroma (SARS) un 2019. gada koronavīrusa slimības (COVID-19) uzliesmojumi, ko izraisīja attiecīgi SARS-CoV un SARS-CoV-2, ir ārkārtīgi apdraudējuši pasaules sabiedrības labklājību un ekonomisko sistēmu. Šo vīrusu slimību terapija un profilakse ir cilvēka neitralizējošo monoklonālo antivielu (NMAbs) analīze un augšana.

Zinātnieki ir skrīnējuši neitralizējošās antivielas, kā antigēnu izmantojot vīrusa receptoru saistošo zonu (RBD), norādot, ka RBD ir iekļauti vairāki konformācijas neitralizējoši epitopi, kas ir galvenie strukturālie domēni neitralizējošo antivielu un T-šūnu imūnreakciju inducēšanai. Šajā novērtējumā ir apkopota RBD un RBD specifisko NMAb konstrukcija un veiktspēja, pretstatā SARS-CoV un SARS-CoV-2 pašlaik zem izaugsmes.

bernsklepo
bernsklepo

Equine Interleukin 8 (IL8) ELISA Kit

DLR-IL8-Eq-48T 48T
EUR 603.6
Description: A sandwich quantitative ELISA assay kit for detection of Equine Interleukin 8 (IL8) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Equine Interleukin 8 (IL8) ELISA Kit

DLR-IL8-Eq-96T 96T
EUR 784.8
Description: A sandwich quantitative ELISA assay kit for detection of Equine Interleukin 8 (IL8) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Fish Interleukin 8 (IL8) ELISA Kit

DLR-IL8-Fi-48T 48T
EUR 603.6
Description: A sandwich quantitative ELISA assay kit for detection of Fish Interleukin 8 (IL8) in samples from serum, plasma, tissue homogenates or other biological fluids.

Fish Interleukin 8 (IL8) ELISA Kit

DLR-IL8-Fi-96T 96T
EUR 784.8
Description: A sandwich quantitative ELISA assay kit for detection of Fish Interleukin 8 (IL8) in samples from serum, plasma, tissue homogenates or other biological fluids.

Human Interleukin 8 (IL8) ELISA Kit

DLR-IL8-Hu-48T 48T
EUR 399.6
Description: A sandwich quantitative ELISA assay kit for detection of Human Interleukin 8 (IL8) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Human Interleukin 8 (IL8) ELISA Kit

DLR-IL8-Hu-96T 96T
EUR 504
Description: A sandwich quantitative ELISA assay kit for detection of Human Interleukin 8 (IL8) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Porcine Interleukin 8 (IL8) ELISA Kit

DLR-IL8-p-48T 48T
EUR 537.6
Description: A sandwich quantitative ELISA assay kit for detection of Porcine Interleukin 8 (IL8) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Porcine Interleukin 8 (IL8) ELISA Kit

DLR-IL8-p-96T 96T
EUR 694.8
Description: A sandwich quantitative ELISA assay kit for detection of Porcine Interleukin 8 (IL8) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Rabbit Interleukin 8 (IL8) ELISA Kit

DLR-IL8-Rb-48T 48T
EUR 544.8
Description: A sandwich quantitative ELISA assay kit for detection of Rabbit Interleukin 8 (IL8) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Rabbit Interleukin 8 (IL8) ELISA Kit

DLR-IL8-Rb-96T 96T
EUR 704.4
Description: A sandwich quantitative ELISA assay kit for detection of Rabbit Interleukin 8 (IL8) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Monkey Interleukin 8 (IL8) ELISA Kit

DLR-IL8-Si-48T 48T
EUR 568.8
Description: A sandwich quantitative ELISA assay kit for detection of Monkey Interleukin 8 (IL8) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Monkey Interleukin 8 (IL8) ELISA Kit

DLR-IL8-Si-96T 96T
EUR 736.8
Description: A sandwich quantitative ELISA assay kit for detection of Monkey Interleukin 8 (IL8) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Bovine Interleukin 8 (IL8) ELISA Kit

RDR-IL8-b-48Tests 48 Tests
EUR 490.8

Bovine Interleukin 8 (IL8) ELISA Kit

RDR-IL8-b-96Tests 96 Tests
EUR 675.6

Canine Interleukin 8 (IL8) ELISA Kit

RDR-IL8-c-48Tests 48 Tests
EUR 381.6

Canine Interleukin 8 (IL8) ELISA Kit

RDR-IL8-c-96Tests 96 Tests
EUR 519.6

Chicken Interleukin 8 (IL8) ELISA Kit

RDR-IL8-Ch-48Tests 48 Tests
EUR 506.4

Chicken Interleukin 8 (IL8) ELISA Kit

RDR-IL8-Ch-96Tests 96 Tests
EUR 697.2

Equine Interleukin 8 (IL8) ELISA Kit

RDR-IL8-Eq-48Tests 48 Tests
EUR 633.6

Equine Interleukin 8 (IL8) ELISA Kit

RDR-IL8-Eq-96Tests 96 Tests
EUR 879.6

Fish Interleukin 8 (IL8) ELISA Kit

RDR-IL8-Fi-48Tests 48 Tests
EUR 633.6

Fish Interleukin 8 (IL8) ELISA Kit

RDR-IL8-Fi-96Tests 96 Tests
EUR 879.6

Human Interleukin 8 (IL8) ELISA Kit

RDR-IL8-Hu-48Tests 48 Tests
EUR 391.2

Human Interleukin 8 (IL8) ELISA Kit

RDR-IL8-Hu-96Tests 96 Tests
EUR 534

Porcine Interleukin 8 (IL8) ELISA Kit

RDR-IL8-p-48Tests 48 Tests
EUR 555.6

Porcine Interleukin 8 (IL8) ELISA Kit

RDR-IL8-p-96Tests 96 Tests
EUR 768

Rabbit Interleukin 8 (IL8) ELISA Kit

RDR-IL8-Rb-48Tests 48 Tests
EUR 564

Rabbit Interleukin 8 (IL8) ELISA Kit

RDR-IL8-Rb-96Tests 96 Tests
EUR 781.2

Monkey Interleukin 8 (IL8) ELISA Kit

RDR-IL8-Si-48Tests 48 Tests
EUR 591.6

Monkey Interleukin 8 (IL8) ELISA Kit

RDR-IL8-Si-96Tests 96 Tests
EUR 819.6

Bovine Interleukin 8 (IL8) ELISA Kit

RD-IL8-b-48Tests 48 Tests
EUR 470.4

Bovine Interleukin 8 (IL8) ELISA Kit

RD-IL8-b-96Tests 96 Tests
EUR 646.8

Canine Interleukin 8 (IL8) ELISA Kit

RD-IL8-c-48Tests 48 Tests
EUR 366

Canine Interleukin 8 (IL8) ELISA Kit

RD-IL8-c-96Tests 96 Tests
EUR 498

Chicken Interleukin 8 (IL8) ELISA Kit

RD-IL8-Ch-48Tests 48 Tests
EUR 484.8

Chicken Interleukin 8 (IL8) ELISA Kit

RD-IL8-Ch-96Tests 96 Tests
EUR 667.2

Equine Interleukin 8 (IL8) ELISA Kit

RD-IL8-Eq-48Tests 48 Tests
EUR 606

Equine Interleukin 8 (IL8) ELISA Kit

RD-IL8-Eq-96Tests 96 Tests
EUR 840

Human Interleukin 8 (IL8) ELISA Kit

RD-IL8-Hu-48Tests 48 Tests
EUR 375.6

Human Interleukin 8 (IL8) ELISA Kit

RD-IL8-Hu-96Tests 96 Tests
EUR 511.2

Porcine Interleukin 8 (IL8) ELISA Kit

RD-IL8-p-48Tests 48 Tests
EUR 531.6

Porcine Interleukin 8 (IL8) ELISA Kit

RD-IL8-p-96Tests 96 Tests
EUR 734.4

Rabbit Interleukin 8 (IL8) ELISA Kit

RD-IL8-Rb-48Tests 48 Tests
EUR 540

Rabbit Interleukin 8 (IL8) ELISA Kit

RD-IL8-Rb-96Tests 96 Tests
EUR 746.4

Monkey Interleukin 8 (IL8) ELISA Kit

RD-IL8-Si-48Tests 48 Tests
EUR 566.4

Monkey Interleukin 8 (IL8) ELISA Kit

RD-IL8-Si-96Tests 96 Tests
EUR 783.6

Interleukin 8 (IL8) Monoclonal Antibody (Horse)

4-MAA080Eq21
  • EUR 325.20
  • EUR 3470.40
  • EUR 854.40
  • EUR 412.80
  • EUR 268.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Horse Interleukin 8 (IL8)

Interleukin 8 (IL8) Monoclonal Antibody (Chicken)

4-MAA080Ga22
  • EUR 283.20
  • EUR 2805.60
  • EUR 703.20
  • EUR 352.80
  • EUR 250.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Chicken Interleukin 8 (IL8)

Interleukin 8 (IL8) Monoclonal Antibody (Human)

4-MAA080Hu22
  • EUR 265.20
  • EUR 2536.80
  • EUR 642.00
  • EUR 328.80
  • EUR 243.60
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Human Interleukin 8 (IL8)

Interleukin 8 (IL8) Monoclonal Antibody (Human)

4-MAA080Hu24
  • EUR 265.20
  • EUR 2536.80
  • EUR 642.00
  • EUR 328.80
  • EUR 243.60
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Human Interleukin 8 (IL8)

Interleukin 8 (IL8) Monoclonal Antibody (Pig)

4-MAA080Po22
  • EUR 298.80
  • EUR 3058.80
  • EUR 760.80
  • EUR 375.60
  • EUR 258.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Pig Interleukin 8 (IL8)

Interleukin 8 (IL8) Monoclonal Antibody (Pig)

4-MAA080Po24
  • EUR 298.80
  • EUR 3058.80
  • EUR 760.80
  • EUR 375.60
  • EUR 258.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Pig Interleukin 8 (IL8)

Interleukin 8 (IL8) Monoclonal Antibody (Pig)

4-MAA080Po26
  • EUR 298.80
  • EUR 3058.80
  • EUR 760.80
  • EUR 375.60
  • EUR 258.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Pig Interleukin 8 (IL8)

Interleukin 8 (IL8) Monoclonal Antibody (Rabbit)

4-MAA080Rb22
  • EUR 301.20
  • EUR 3106.80
  • EUR 771.60
  • EUR 380.40
  • EUR 259.20
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Rabbit Interleukin 8 (IL8)

Guinea pig Interleukin 8 (IL8) ELISA Kit

DLR-IL8-Gu-48T 48T
EUR 465.6
Description: A sandwich quantitative ELISA assay kit for detection of Guinea pig Interleukin 8 (IL8) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Guinea pig Interleukin 8 (IL8) ELISA Kit

DLR-IL8-Gu-96T 96T
EUR 595.2
Description: A sandwich quantitative ELISA assay kit for detection of Guinea pig Interleukin 8 (IL8) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Guinea pig Interleukin 8 (IL8) ELISA Kit

RDR-IL8-Gu-48Tests 48 Tests
EUR 469.2

Guinea pig Interleukin 8 (IL8) ELISA Kit

RDR-IL8-Gu-96Tests 96 Tests
EUR 645.6

Guinea pig Interleukin 8 (IL8) ELISA Kit

RD-IL8-Gu-48Tests 48 Tests
EUR 450

Guinea pig Interleukin 8 (IL8) ELISA Kit

RD-IL8-Gu-96Tests 96 Tests
EUR 618

Interleukin 8 (IL8) Antibody

20-abx137023
  • EUR 427.20
  • EUR 627.60
  • 0.5 mg
  • 1 mg

Interleukin 8 (IL8) Antibody

20-abx100960
  • EUR 376.80
  • EUR 159.60
  • EUR 994.80
  • EUR 510.00
  • EUR 326.40
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Interleukin 8 (IL8) Antibody

20-abx100961
  • EUR 493.20
  • EUR 159.60
  • EUR 1345.20
  • EUR 661.20
  • EUR 376.80
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Interleukin 8 (IL8) Antibody

20-abx100962
  • EUR 493.20
  • EUR 159.60
  • EUR 1345.20
  • EUR 661.20
  • EUR 376.80
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Interleukin 8 (IL8) Antibody

20-abx100963
  • EUR 360.00
  • EUR 844.80
  • EUR 427.20
  • EUR 184.80
  • EUR 292.80
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Interleukin 8 (IL8) Antibody

20-abx100964
  • EUR 360.00
  • EUR 844.80
  • EUR 427.20
  • EUR 184.80
  • EUR 292.80
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Interleukin 8 (IL8) Antibody

20-abx100965
  • EUR 477.60
  • EUR 159.60
  • EUR 1279.20
  • EUR 627.60
  • EUR 360.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Interleukin 8 (IL8) Antibody

20-abx100966
  • EUR 376.80
  • EUR 927.60
  • EUR 493.20
  • EUR 184.80
  • EUR 309.60
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Interleukin 8 (IL8) Antibody

20-abx100967
  • EUR 493.20
  • EUR 159.60
  • EUR 1395.60
  • EUR 678.00
  • EUR 376.80
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Interleukin 8 (IL8) Antibody

20-abx100969
  • EUR 526.80
  • EUR 159.60
  • EUR 1479.60
  • EUR 710.40
  • EUR 393.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Interleukin 8 (IL8) Antibody

20-abx100970
  • EUR 410.40
  • EUR 1045.20
  • EUR 543.60
  • EUR 184.80
  • EUR 326.40
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Interleukin 8 (IL8) Antibody

20-abx100971
  • EUR 543.60
  • EUR 159.60
  • EUR 1579.20
  • EUR 760.80
  • EUR 410.40
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Interleukin 8 (IL8) Antibody

20-abx100972
  • EUR 560.40
  • EUR 159.60
  • EUR 1646.40
  • EUR 777.60
  • EUR 427.20
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Interleukin 8 (IL8) Antibody

20-abx009111
  • EUR 360.00
  • EUR 526.80
  • EUR 226.80
  • 100 ul
  • 200 ul
  • 30 ul

Interleukin 8 (IL8) Antibody

20-abx131832
  • EUR 427.20
  • EUR 1111.20
  • EUR 560.40
  • EUR 184.80
  • EUR 326.40
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Interleukin 8 (IL8) Antibody

20-abx131833
  • EUR 410.40
  • EUR 1045.20
  • EUR 543.60
  • EUR 184.80
  • EUR 326.40
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Interleukin 8 (IL8) Antibody

20-abx131834
  • EUR 393.60
  • EUR 994.80
  • EUR 510.00
  • EUR 184.80
  • EUR 309.60
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Interleukin 8 (IL8) Antibody

20-abx131835
  • EUR 393.60
  • EUR 1011.60
  • EUR 526.80
  • EUR 184.80
  • EUR 309.60
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Interleukin 8 (IL8) Antibody

20-abx131836
  • EUR 410.40
  • EUR 1045.20
  • EUR 543.60
  • EUR 184.80
  • EUR 326.40
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Interleukin 8 (IL8) Antibody

20-abx131837
  • EUR 410.40
  • EUR 1045.20
  • EUR 543.60
  • EUR 184.80
  • EUR 326.40
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Interleukin 8 (IL8) Antibody

20-abx131838
  • EUR 360.00
  • EUR 844.80
  • EUR 427.20
  • EUR 184.80
  • EUR 292.80
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Interleukin 8 (IL8) Antibody

20-abx131839
  • EUR 393.60
  • EUR 994.80
  • EUR 510.00
  • EUR 184.80
  • EUR 309.60
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Interleukin 8 (IL8) Antibody

20-abx131840
  • EUR 393.60
  • EUR 994.80
  • EUR 510.00
  • EUR 184.80
  • EUR 309.60
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Interleukin 8 (IL8) Antibody

abx018002-100ug 100 ug
EUR 410.4

Interleukin 8 (IL8) Antibody

abx020956-05mg 0.5 mg
EUR 1296

Interleukin 8 (IL8) Antibody

abx036426-100ug 100 ug
EUR 469.2

Interleukin 8 (IL8) Antibody

20-abx270103
  • EUR 560.40
  • EUR 644.40
  • EUR 326.40
  • EUR 978.00
  • EUR 427.20
  • 100 tests
  • 200 tests
  • 25 tests
  • 500 tests
  • 50 tests

Interleukin 8 (IL8) Antibody

20-abx270152
  • EUR 560.40
  • EUR 644.40
  • EUR 326.40
  • EUR 978.00
  • EUR 427.20
  • 100 tests
  • 200 tests
  • 25 tests
  • 500 tests
  • 50 tests

Interleukin 8 (IL8) Antibody

20-abx270200
  • EUR 560.40
  • EUR 644.40
  • EUR 326.40
  • EUR 978.00
  • EUR 427.20
  • 100 tests
  • 200 tests
  • 25 tests
  • 500 tests
  • 50 tests

Interleukin 8 (IL8) Antibody

20-abx270201
  • EUR 560.40
  • EUR 644.40
  • EUR 326.40
  • EUR 978.00
  • EUR 427.20
  • 100 tests
  • 200 tests
  • 25 tests
  • 500 tests
  • 50 tests

Interleukin 8 (IL8) Antibody

abx216289-100ug 100 ug
EUR 526.8

Interleukin 8 (IL8) Antibody

20-abx173191
  • EUR 427.20
  • EUR 1095.60
  • EUR 560.40
  • EUR 184.80
  • EUR 326.40
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Interleukin 8 (IL8) Antibody

20-abx177199
  • EUR 427.20
  • EUR 159.60
  • EUR 1245.60
  • EUR 627.60
  • EUR 360.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Interleukin 8 (IL8) Antibody

20-abx177201
  • EUR 1429.20
  • EUR 693.60
  • 1 mg
  • 200 ug

Interleukin 8 (IL8) Monoclonal Antibody (Human, Dog)

4-MAA080Ca22
  • EUR 265.20
  • EUR 2536.80
  • EUR 642.00
  • EUR 328.80
  • EUR 243.60
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Human, Dog Interleukin 8 (IL8)

Interleukin 8 (IL8) Monoclonal Antibody (Horse), APC

4-MAA080Eq21-APC
  • EUR 458.40
  • EUR 4556.40
  • EUR 1251.60
  • EUR 590.40
  • EUR 280.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Horse Interleukin 8 (IL8). This antibody is labeled with APC.

Interleukin 8 (IL8) Monoclonal Antibody (Horse), Biotinylated

4-MAA080Eq21-Biotin
  • EUR 405.60
  • EUR 3410.40
  • EUR 987.60
  • EUR 502.80
  • EUR 276.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Horse Interleukin 8 (IL8). This antibody is labeled with Biotin.

Interleukin 8 (IL8) Monoclonal Antibody (Horse), Cy3

4-MAA080Eq21-Cy3
  • EUR 561.60
  • EUR 6025.20
  • EUR 1618.80
  • EUR 736.80
  • EUR 325.20
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Horse Interleukin 8 (IL8). This antibody is labeled with Cy3.

Interleukin 8 (IL8) Monoclonal Antibody (Horse), FITC

4-MAA080Eq21-FITC
  • EUR 390.00
  • EUR 3668.40
  • EUR 1024.80
  • EUR 495.60
  • EUR 248.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Horse Interleukin 8 (IL8). This antibody is labeled with FITC.

Interleukin 8 (IL8) Monoclonal Antibody (Horse), HRP

4-MAA080Eq21-HRP
  • EUR 417.60
  • EUR 3968.40
  • EUR 1104.00
  • EUR 531.60
  • EUR 264.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Horse Interleukin 8 (IL8). This antibody is labeled with HRP.

Interleukin 8 (IL8) Monoclonal Antibody (Horse), PE

4-MAA080Eq21-PE
  • EUR 390.00
  • EUR 3668.40
  • EUR 1024.80
  • EUR 495.60
  • EUR 248.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Horse Interleukin 8 (IL8). This antibody is labeled with PE.

Interleukin 8 (IL8) Monoclonal Antibody (Chicken), APC

4-MAA080Ga22-APC
  • EUR 394.80
  • EUR 3649.20
  • EUR 1024.80
  • EUR 499.20
  • EUR 254.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Chicken Interleukin 8 (IL8). This antibody is labeled with APC.

Interleukin 8 (IL8) Monoclonal Antibody (Chicken), Biotinylated

4-MAA080Ga22-Biotin
  • EUR 358.80
  • EUR 2745.60
  • EUR 820.80
  • EUR 435.60
  • EUR 256.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Chicken Interleukin 8 (IL8). This antibody is labeled with Biotin.

Interleukin 8 (IL8) Monoclonal Antibody (Chicken), Cy3

4-MAA080Ga22-Cy3
  • EUR 476.40
  • EUR 4815.60
  • EUR 1316.40
  • EUR 615.60
  • EUR 289.20
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Chicken Interleukin 8 (IL8). This antibody is labeled with Cy3.

Interleukin 8 (IL8) Monoclonal Antibody (Chicken), FITC

4-MAA080Ga22-FITC
  • EUR 339.60
  • EUR 2942.40
  • EUR 843.60
  • EUR 423.60
  • EUR 226.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Chicken Interleukin 8 (IL8). This antibody is labeled with FITC.

Interleukin 8 (IL8) Monoclonal Antibody (Chicken), HRP

4-MAA080Ga22-HRP
  • EUR 362.40
  • EUR 3182.40
  • EUR 907.20
  • EUR 452.40
  • EUR 240.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Chicken Interleukin 8 (IL8). This antibody is labeled with HRP.

Interleukin 8 (IL8) Monoclonal Antibody (Chicken), PE

4-MAA080Ga22-PE
  • EUR 339.60
  • EUR 2942.40
  • EUR 843.60
  • EUR 423.60
  • EUR 226.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Chicken Interleukin 8 (IL8). This antibody is labeled with PE.

Interleukin 8 (IL8) Monoclonal Antibody (Guinea pig)

4-MAA080Gu21
  • EUR 310.80
  • EUR 3249.60
  • EUR 804.00
  • EUR 393.60
  • EUR 262.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Guinea pig Interleukin 8 (IL8)

Interleukin 8 (IL8) Monoclonal Antibody (Guinea pig)

4-MAA080Gu24
  • EUR 310.80
  • EUR 3249.60
  • EUR 804.00
  • EUR 393.60
  • EUR 262.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Guinea pig Interleukin 8 (IL8)

Interleukin 8 (IL8) Monoclonal Antibody (Human), APC

4-MAA080Hu22-APC
  • EUR 368.40
  • EUR 3282.00
  • EUR 932.40
  • EUR 463.20
  • EUR 243.60
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Human Interleukin 8 (IL8). This antibody is labeled with APC.

Interleukin 8 (IL8) Monoclonal Antibody (Human), Biotinylated

4-MAA080Hu22-Biotin
  • EUR 339.60
  • EUR 2476.80
  • EUR 753.60
  • EUR 409.20
  • EUR 248.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Human Interleukin 8 (IL8). This antibody is labeled with Biotin.

Interleukin 8 (IL8) Monoclonal Antibody (Human), Cy3

4-MAA080Hu22-Cy3
  • EUR 441.60
  • EUR 4326.00
  • EUR 1194.00
  • EUR 567.60
  • EUR 274.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Human Interleukin 8 (IL8). This antibody is labeled with Cy3.

Interleukin 8 (IL8) Monoclonal Antibody (Human), FITC

4-MAA080Hu22-FITC
  • EUR 319.20
  • EUR 2649.60
  • EUR 770.40
  • EUR 393.60
  • EUR 218.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Human Interleukin 8 (IL8). This antibody is labeled with FITC.

Interleukin 8 (IL8) Monoclonal Antibody (Human), HRP

4-MAA080Hu22-HRP
  • EUR 339.60
  • EUR 2864.40
  • EUR 828.00
  • EUR 421.20
  • EUR 230.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Human Interleukin 8 (IL8). This antibody is labeled with HRP.

Interleukin 8 (IL8) Monoclonal Antibody (Human), PE

4-MAA080Hu22-PE
  • EUR 319.20
  • EUR 2649.60
  • EUR 770.40
  • EUR 393.60
  • EUR 218.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Human Interleukin 8 (IL8). This antibody is labeled with PE.

Interleukin 8 (IL8) Monoclonal Antibody (Human), APC

4-MAA080Hu24-APC
  • EUR 368.40
  • EUR 3282.00
  • EUR 932.40
  • EUR 463.20
  • EUR 243.60
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Human Interleukin 8 (IL8). This antibody is labeled with APC.

Interleukin 8 (IL8) Monoclonal Antibody (Human), Biotinylated

4-MAA080Hu24-Biotin
  • EUR 339.60
  • EUR 2476.80
  • EUR 753.60
  • EUR 409.20
  • EUR 248.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Human Interleukin 8 (IL8). This antibody is labeled with Biotin.

Interleukin 8 (IL8) Monoclonal Antibody (Human), Cy3

4-MAA080Hu24-Cy3
  • EUR 441.60
  • EUR 4326.00
  • EUR 1194.00
  • EUR 567.60
  • EUR 274.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Human Interleukin 8 (IL8). This antibody is labeled with Cy3.

Interleukin 8 (IL8) Monoclonal Antibody (Human), FITC

4-MAA080Hu24-FITC
  • EUR 319.20
  • EUR 2649.60
  • EUR 770.40
  • EUR 393.60
  • EUR 218.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Human Interleukin 8 (IL8). This antibody is labeled with FITC.

Interleukin 8 (IL8) Monoclonal Antibody (Human), HRP

4-MAA080Hu24-HRP
  • EUR 339.60
  • EUR 2864.40
  • EUR 828.00
  • EUR 421.20
  • EUR 230.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Human Interleukin 8 (IL8). This antibody is labeled with HRP.

Interleukin 8 (IL8) Monoclonal Antibody (Human), PE

4-MAA080Hu24-PE
  • EUR 319.20
  • EUR 2649.60
  • EUR 770.40
  • EUR 393.60
  • EUR 218.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Human Interleukin 8 (IL8). This antibody is labeled with PE.

Interleukin 8 (IL8) Monoclonal Antibody (Pig), APC

4-MAA080Po22-APC
  • EUR 418.80
  • EUR 3994.80
  • EUR 1111.20
  • EUR 534.00
  • EUR 265.20
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Pig Interleukin 8 (IL8). This antibody is labeled with APC.

Interleukin 8 (IL8) Monoclonal Antibody (Pig), Biotinylated

4-MAA080Po22-Biotin
  • EUR 376.80
  • EUR 2998.80
  • EUR 884.40
  • EUR 460.80
  • EUR 264.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Pig Interleukin 8 (IL8). This antibody is labeled with Biotin.

Interleukin 8 (IL8) Monoclonal Antibody (Pig), Cy3

4-MAA080Po22-Cy3
  • EUR 507.60
  • EUR 5276.40
  • EUR 1431.60
  • EUR 662.40
  • EUR 303.60
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Pig Interleukin 8 (IL8). This antibody is labeled with Cy3.

Interleukin 8 (IL8) Monoclonal Antibody (Pig), FITC

4-MAA080Po22-FITC
  • EUR 358.80
  • EUR 3219.60
  • EUR 912.00
  • EUR 451.20
  • EUR 236.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Pig Interleukin 8 (IL8). This antibody is labeled with FITC.

Interleukin 8 (IL8) Monoclonal Antibody (Pig), HRP

4-MAA080Po22-HRP
  • EUR 382.80
  • EUR 3481.20
  • EUR 982.80
  • EUR 482.40
  • EUR 249.60
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Pig Interleukin 8 (IL8). This antibody is labeled with HRP.

Interleukin 8 (IL8) Monoclonal Antibody (Pig), PE

4-MAA080Po22-PE
  • EUR 358.80
  • EUR 3219.60
  • EUR 912.00
  • EUR 451.20
  • EUR 236.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Pig Interleukin 8 (IL8). This antibody is labeled with PE.

Interleukin 8 (IL8) Monoclonal Antibody (Pig), APC

4-MAA080Po24-APC
  • EUR 418.80
  • EUR 3994.80
  • EUR 1111.20
  • EUR 534.00
  • EUR 265.20
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Pig Interleukin 8 (IL8). This antibody is labeled with APC.

Interleukin 8 (IL8) Monoclonal Antibody (Pig), Biotinylated

4-MAA080Po24-Biotin
  • EUR 376.80
  • EUR 2998.80
  • EUR 884.40
  • EUR 460.80
  • EUR 264.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Pig Interleukin 8 (IL8). This antibody is labeled with Biotin.

Interleukin 8 (IL8) Monoclonal Antibody (Pig), Cy3

4-MAA080Po24-Cy3
  • EUR 507.60
  • EUR 5276.40
  • EUR 1431.60
  • EUR 662.40
  • EUR 303.60
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Pig Interleukin 8 (IL8). This antibody is labeled with Cy3.

Interleukin 8 (IL8) Monoclonal Antibody (Pig), FITC

4-MAA080Po24-FITC
  • EUR 358.80
  • EUR 3219.60
  • EUR 912.00
  • EUR 451.20
  • EUR 236.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Pig Interleukin 8 (IL8). This antibody is labeled with FITC.

Interleukin 8 (IL8) Monoclonal Antibody (Pig), HRP

4-MAA080Po24-HRP
  • EUR 382.80
  • EUR 3481.20
  • EUR 982.80
  • EUR 482.40
  • EUR 249.60
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Pig Interleukin 8 (IL8). This antibody is labeled with HRP.

Interleukin 8 (IL8) Monoclonal Antibody (Pig), PE

4-MAA080Po24-PE
  • EUR 358.80
  • EUR 3219.60
  • EUR 912.00
  • EUR 451.20
  • EUR 236.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Pig Interleukin 8 (IL8). This antibody is labeled with PE.

Interleukin 8 (IL8) Monoclonal Antibody (Pig), APC

4-MAA080Po26-APC
  • EUR 418.80
  • EUR 3994.80
  • EUR 1111.20
  • EUR 534.00
  • EUR 265.20
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Pig Interleukin 8 (IL8). This antibody is labeled with APC.

Interleukin 8 (IL8) Monoclonal Antibody (Pig), Biotinylated

4-MAA080Po26-Biotin
  • EUR 376.80
  • EUR 2998.80
  • EUR 884.40
  • EUR 460.80
  • EUR 264.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Pig Interleukin 8 (IL8). This antibody is labeled with Biotin.

Interleukin 8 (IL8) Monoclonal Antibody (Pig), Cy3

4-MAA080Po26-Cy3
  • EUR 507.60
  • EUR 5276.40
  • EUR 1431.60
  • EUR 662.40
  • EUR 303.60
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Pig Interleukin 8 (IL8). This antibody is labeled with Cy3.

Interleukin 8 (IL8) Monoclonal Antibody (Pig), FITC

4-MAA080Po26-FITC
  • EUR 358.80
  • EUR 3219.60
  • EUR 912.00
  • EUR 451.20
  • EUR 236.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Pig Interleukin 8 (IL8). This antibody is labeled with FITC.

Interleukin 8 (IL8) Monoclonal Antibody (Pig), HRP

4-MAA080Po26-HRP
  • EUR 382.80
  • EUR 3481.20
  • EUR 982.80
  • EUR 482.40
  • EUR 249.60
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Pig Interleukin 8 (IL8). This antibody is labeled with HRP.

Interleukin 8 (IL8) Monoclonal Antibody (Pig), PE

4-MAA080Po26-PE
  • EUR 358.80
  • EUR 3219.60
  • EUR 912.00
  • EUR 451.20
  • EUR 236.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Pig Interleukin 8 (IL8). This antibody is labeled with PE.

Interleukin 8 (IL8) Monoclonal Antibody (Rabbit), APC

4-MAA080Rb22-APC
  • EUR 422.40
  • EUR 4059.60
  • EUR 1126.80
  • EUR 540.00
  • EUR 267.60
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Rabbit Interleukin 8 (IL8). This antibody is labeled with APC.

Interleukin 8 (IL8) Monoclonal Antibody (Rabbit), Biotinylated

4-MAA080Rb22-Biotin
  • EUR 379.20
  • EUR 3046.80
  • EUR 896.40
  • EUR 465.60
  • EUR 265.20
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Rabbit Interleukin 8 (IL8). This antibody is labeled with Biotin.

Interleukin 8 (IL8) Monoclonal Antibody (Rabbit), Cy3

4-MAA080Rb22-Cy3
  • EUR 513.60
  • EUR 5362.80
  • EUR 1453.20
  • EUR 670.80
  • EUR 306.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Rabbit Interleukin 8 (IL8). This antibody is labeled with Cy3.

Interleukin 8 (IL8) Monoclonal Antibody (Rabbit), FITC

4-MAA080Rb22-FITC
  • EUR 362.40
  • EUR 3271.20
  • EUR 925.20
  • EUR 456.00
  • EUR 237.60
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Rabbit Interleukin 8 (IL8). This antibody is labeled with FITC.

Interleukin 8 (IL8) Monoclonal Antibody (Rabbit), HRP

4-MAA080Rb22-HRP
  • EUR 386.40
  • EUR 3537.60
  • EUR 996.00
  • EUR 488.40
  • EUR 252.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Rabbit Interleukin 8 (IL8). This antibody is labeled with HRP.

Interleukin 8 (IL8) Monoclonal Antibody (Rabbit), PE

4-MAA080Rb22-PE
  • EUR 362.40
  • EUR 3271.20
  • EUR 925.20
  • EUR 456.00
  • EUR 237.60
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Rabbit Interleukin 8 (IL8). This antibody is labeled with PE.

Interleukin 8 (IL8) Monoclonal Antibody (Rhesus monkey)

4-MAA080Si21
  • EUR 310.80
  • EUR 3249.60
  • EUR 804.00
  • EUR 393.60
  • EUR 262.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Rhesus monkey Interleukin 8 (IL8)

Interleukin 8 (IL8) Monoclonal Antibody (Rhesus monkey)

4-MAA080Si22
  • EUR 310.80
  • EUR 3249.60
  • EUR 804.00
  • EUR 393.60
  • EUR 262.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Rhesus monkey Interleukin 8 (IL8)

Interleukin 8 (IL8) Monoclonal Antibody (Human, Dog), APC

4-MAA080Ca22-APC
  • EUR 368.40
  • EUR 3282.00
  • EUR 932.40
  • EUR 463.20
  • EUR 243.60
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Human, Dog Interleukin 8 (IL8). This antibody is labeled with APC.

Interleukin 8 (IL8) Monoclonal Antibody (Human, Dog), Biotinylated

4-MAA080Ca22-Biotin
  • EUR 339.60
  • EUR 2476.80
  • EUR 753.60
  • EUR 409.20
  • EUR 248.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Human, Dog Interleukin 8 (IL8). This antibody is labeled with Biotin.

Interleukin 8 (IL8) Monoclonal Antibody (Human, Dog), Cy3

4-MAA080Ca22-Cy3
  • EUR 441.60
  • EUR 4326.00
  • EUR 1194.00
  • EUR 567.60
  • EUR 274.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Human, Dog Interleukin 8 (IL8). This antibody is labeled with Cy3.

Interleukin 8 (IL8) Monoclonal Antibody (Human, Dog), FITC

4-MAA080Ca22-FITC
  • EUR 319.20
  • EUR 2649.60
  • EUR 770.40
  • EUR 393.60
  • EUR 218.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Human, Dog Interleukin 8 (IL8). This antibody is labeled with FITC.

Interleukin 8 (IL8) Monoclonal Antibody (Human, Dog), HRP

4-MAA080Ca22-HRP
  • EUR 339.60
  • EUR 2864.40
  • EUR 828.00
  • EUR 421.20
  • EUR 230.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Human, Dog Interleukin 8 (IL8). This antibody is labeled with HRP.

Interleukin 8 (IL8) Monoclonal Antibody (Human, Dog), PE

4-MAA080Ca22-PE
  • EUR 319.20
  • EUR 2649.60
  • EUR 770.40
  • EUR 393.60
  • EUR 218.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Human, Dog Interleukin 8 (IL8). This antibody is labeled with PE.

Interleukin 8 (IL8) Monoclonal Antibody (Horse), APC-Cy7

4-MAA080Eq21-APC-Cy7
  • EUR 772.80
  • EUR 8968.80
  • EUR 2359.20
  • EUR 1036.80
  • EUR 418.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Horse Interleukin 8 (IL8). This antibody is labeled with APC-Cy7.

Interleukin 8 (IL8) Monoclonal Antibody (Chicken), APC-Cy7

4-MAA080Ga22-APC-Cy7
  • EUR 645.60
  • EUR 7154.40
  • EUR 1905.60
  • EUR 855.60
  • EUR 364.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Chicken Interleukin 8 (IL8). This antibody is labeled with APC-Cy7.

MET un RON receptoru tirozīna kināzes kolorektālajā adenokarcinomā: molekulāras iespējas kā zāļu mērķi un antivielu un zāļu konjugāti ārstēšanai

Augstākā kolorektālā adenokarcinoma (CRAC), ko raksturo atšķirīgs histopatoloģisks izskats, tālu orgānu metastāzes, iegūta ķīmijrezistence un audzēja ģenētiskais stublājs, ir daudz neviendabīgu vēžu ar atšķirīgiem ģenētiskiem parakstiem un ļaundabīgiem fenotipiem. CRAC terapija onkologiem ir biedējoša darbība.

Šobrīd cīņā pret šo letālo slimību ir izmantotas daudzas metodes kopā ar molekulāro koncentrēšanos uz terapeitisko monoklonālo antivielu, mazmolekulāro kināzes inhibitoru un imūnregulācijas kontrolpunkta līdzekli. Tomēr šīs terapeitiskās metodes un pieejas gūst tikai ierobežotus panākumus. Tādējādi farmaceitiski vēlas atrast jaunus mērķus un izstrādāt jaunus CRAC līdzekļa terapijas līdzekļus. MET un RON receptoru tirozīna kināzes ir iesaistītas CRAC patoģenēzē.

Zinātniskie pētījumi ir atklājuši, ka novirzīta MET un / vai RON ekspresija un signalizācija ir būtiska, regulējot CRAC attīstību un ļaundabīgos fenotipus. Paaugstinātai MET un / vai RON izteiksmei ir arī CRAC attīstības un skartās personas izdzīvošanas prognozes vērtība.

Šīs iespējas piedāvā loģisko pamatu koncentrēties uz TER un RON zinātniskai CRAC iejaukšanai. Pašlaik, izmantojot mazmolekulārās kināzes inhibitorus, koncentrējoties uz MET CRAC terapijai, ir panākts būtisks progress, saņemot vairākus apstiprinājumus zinātniskai lietošanai.

Neskatoties uz to, uz antivielām balstītie bioterapeitiskie līdzekļi, lai arī zinātniski pētījumi veikti vairāk nekā astoņus gadus, ir guvuši nelielu progresu vai nav devuši nekādu progresu. Šajā novērtējumā mēs koncentrējamies uz MET un / vai RON nozīmi CRAC audzēja veidošanā un anti-MET, anti-RON un MET un RON-dual augšanu, koncentrējoties uz antivielu un zāļu konjugātiem zinātniskai lietderībai. Katra preklīniskā un zinātniskā pētījuma secinājumi agrāk vai vēlāk atklāj šī jaunā veida bioterapeitisko līdzekļu potenciālu CRAC ārstēšanai.

Seruma anti-Neu5Gc antivielu afinitātes attīrīšana atklāja paaugstinātu diapazonu un neobjektīvus masīvu repertuāra modeļus cilvēkiem, kuriem palielinājās Neu5Gc diapazons, bez antivielu afinitātes palielināšanās. Turklāt augsta gaļas svara samazināšanas plānā antivielu daudzveidības modeļi uz glikāna mikroelementiem mainījās ar Neu5Gcα3 saistīto glikānu virzienā, paaugstinot α3 / α6-glikānu attiecību.

Secinājumi: Mēs atklājām pārredzamu hipersaiti starp grādiem un seruma anti-Neu5Gc IgG un Neu5Gc patēriņu no rozā gaļas un piena produktiem. Šīs precīzās racionālās metodikas ļāva izstrādāt Gcemicindeksu, lai vienkāršotu Neu5Gc novērtēšanu ēdienreizēs, kas, bez šaubām, būtu pielāgots uztura ieteikumiem, lai samazinātu lielāko daļu vēža risku.

Antivielu reakcija uz suņu parvovīrusa vakcināciju suņiem ar hiperadrenokortikismu, kas tiek ārstēta ar Trilostane

  • Nav zināms, kā suņi ar hiperadrenokortikismu (HAC) reaģē uz vakcināciju. Šajā pētījumā tika izmērītas antivielas pretstatā suņu parvovīrusam (CPV) suņiem ar HAC, kas ar trilostānu apstrādāts agrāk un pēc CPV vakcinācijas, un atšķirībā no imūnās atbildes reakcijas uz veselīgu suņu reakciju. 
  • Vienpadsmit ilkņi ar HAC un pilnvērtīgi vecumam atbilstoši suņi (n = 31) ieguva modificētu dzīvo CPV vakcīnu. Antivielas ir izlemtas 0., 7. un 28. dienā ar hemaglutinācijas inhibīciju. Lai saskaņotu suņu imūnreakciju ar HAC un pilnvērtīgiem ilkņiem, tika izmantots vienveidīgais novērtējums.
  • Pirmsvakcinācijas antivielas (≥10) ir atklātas 100% suņu ar HAC (11/11; 95% TI: 70,0-100) un 93,5% pilnvērtīgu suņu (29/31; 95% TI: 78,3- 99.2). Suņiem ar HAC netika novērota ≥Four reizes lielāka antivielu titra palielināšanās, turpretī 22,6% pilnvērtīgu ilkņu gadījumā ≥Four reizes titra palielināšanās tika novērota (7/31; 95% TI: 11,1-40,1).
  • Maigi ar vakcīnu saistīti antagonistiski gadījumi (VAAE) ir konstatēti 54,5% suņu ar HAC (6/11; 95% TI: 28,0-78,8) un 29,0% pilnvērtīgu ilkņu (9/31; 95% TI: 15,9) -46,8). Nebija būtiskas atšķirības pirmsvakcinācijas antivielu klātbūtnē (p = 1.000), atbildes reakcija uz vakcināciju (p = 0.161), kā arī VAAE izplatības ziņā (p = 0.158). Imūnsistēmas suņu darbība ar HAC, kas apstrādāta ar trilostānu, šķiet līdzīga veselīgu ilkņu darbībai.

Linkeru izstrāde un validācija vietņu specifiskai antivielu-narkotiku konjugātu sagatavošanai, kas satur vairākas zāļu kopijas vienā cisteīna konjugācijas vietnē

Pirmās paaudzes cisteīna bāzes specifisko antivielu un zāļu konjugāti (ADC) ir ierobežoti līdz 1 narkotikai uz vienu cisteīnu. Neskatoties uz to, noteiktiem mērķiem nepieciešama pārmērīga zāļu un antivielu attiecība (DAR), kas atbilst zemas jaudas kravām. Palielinātu zāļu slodzi var panākt, izmantojot klasiskās cisteīna konjugācijas stratēģijas, tomēr tās noved pie neviendabīguma, neoptimālas efektivitātes un farmakokinētikas.

Šeit mēs aprakstām to heterobifunkcionālo saišu dizainu, sintēzi un apstiprināšanu, kuras var izmantot ADC ar divu, trīs un Four DAR sagatavošanai, katrai vietnei raksturīgā metodē vienā cisteīna konjugācijas vietnē, kas noved pie vietnei specifiskiem ADC ar DAR 4, seši un astoņi. Izstrādātie saites satur sulfhidrilam raksturīgu jodoacetilreaktīvu grupu un vairākas cikliskas diēna daļas, kas, izmantojot Dīla-Aldera reakciju, varētu efektīvi reaģēt ar lietderīgo slodzi ar maleimīdu nesošajām kravām.

 Kā idejas pierādījumu mēs sintezējām vietnei specifiskus DAR 4, sešus un astoņus ADC, kas satur tubulizīnu (AZ13601508), izmantojot inženierijas antivielas ar cisteīnu, kas ievietots aiz 239. vietas antivielu CH2 zonā.

Mēs novērtējām un atšķirībā no tā ADC in vitro citotoksicitāti, kas iegūta, izmantojot šeit aprakstīto vietnei specifisko platformu, ar ADC, kas gatavi izmantot klasisko cisteīna konjugāciju. Mūsu zināšanas apstiprināja jaunu konjugācijas platformu, kuras pamatā ir cisteīns, vietnei specifisku ADC sagatavošanai ar pārmērīgu zāļu slodzi terapeitiskos nolūkos.

 

Mouse Protectin (CD59) ELISA Kit

RDR-CD59-Mu-48Tests 48 Tests
EUR 640.8

Mouse Protectin (CD59) ELISA Kit

RDR-CD59-Mu-96Tests 96 Tests
EUR 890.4

Mouse Protectin (CD59) ELISA Kit

RD-CD59-Mu-48Tests 48 Tests
EUR 613.2

Mouse Protectin (CD59) ELISA Kit

RD-CD59-Mu-96Tests 96 Tests
EUR 850.8

Human Protectin (CD59) ELISA Kit

DLR-CD59-Hu-48T 48T
EUR 597.6
Description: A sandwich quantitative ELISA assay kit for detection of Human Protectin (CD59) in samples from serum, plasma, cell lysates or other biological fluids.

Human Protectin (CD59) ELISA Kit

DLR-CD59-Hu-96T 96T
EUR 776.4
Description: A sandwich quantitative ELISA assay kit for detection of Human Protectin (CD59) in samples from serum, plasma, cell lysates or other biological fluids.

Human Protectin (CD59) ELISA Kit

RDR-CD59-Hu-48Tests 48 Tests
EUR 626.4

Human Protectin (CD59) ELISA Kit

RDR-CD59-Hu-96Tests 96 Tests
EUR 868.8

Human Protectin (CD59) ELISA Kit

RD-CD59-Hu-48Tests 48 Tests
EUR 600

Human Protectin (CD59) ELISA Kit

RD-CD59-Hu-96Tests 96 Tests
EUR 830.4

Mouse Monoclonal Anti-Human CD59, (Biotin) (Clone 1F5) (mouse IgG1)

CD59-B 25 tests
EUR 489.6

Mouse Monoclonal Anti-Human CD59, (FITC) (Clone 1F5) (mouse IgG1)

CD59-F 25 tests
EUR 489.6

Mouse Monoclonal Anti-Human CD59, (PE) (Clone 1F5) (mouse IgG1)

CD59-PE 25 tests
EUR 489.6

Protectin (CD59) Monoclonal Antibody (Rabbit)

4-MAB336Rb21
  • EUR 301.20
  • EUR 3106.80
  • EUR 771.60
  • EUR 380.40
  • EUR 259.20
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Rabbit Protectin (CD59)

Protectin (CD59) Antibody

20-abx100397
  • EUR 493.20
  • EUR 159.60
  • EUR 1378.80
  • EUR 678.00
  • EUR 376.80
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Protectin (CD59) Antibody

20-abx100398
  • EUR 510.00
  • EUR 159.60
  • EUR 1412.40
  • EUR 693.60
  • EUR 393.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Protectin (CD59) Antibody

20-abx100399
  • EUR 526.80
  • EUR 159.60
  • EUR 1496.40
  • EUR 710.40
  • EUR 393.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Protectin (CD59) Antibody

20-abx100400
  • EUR 526.80
  • EUR 159.60
  • EUR 1496.40
  • EUR 710.40
  • EUR 393.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Protectin (CD59) Antibody

20-abx100401
  • EUR 560.40
  • EUR 159.60
  • EUR 1612.80
  • EUR 760.80
  • EUR 427.20
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Protectin (CD59) Antibody

20-abx100402
  • EUR 577.20
  • EUR 159.60
  • EUR 1730.40
  • EUR 811.20
  • EUR 427.20
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Protectin (CD59) Antibody

20-abx109633
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Protectin (CD59) Antibody

20-abx109634
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Protectin (CD59) Antibody

20-abx174238
  • EUR 978.00
  • EUR 510.00
  • 1 mg
  • 200 ug

Protectin (CD59) Antibody

20-abx132385
  • EUR 393.60
  • EUR 1011.60
  • EUR 526.80
  • EUR 184.80
  • EUR 309.60
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Protectin (CD59) Antibody

abx139305-01mg 0.1 mg
EUR 427.2

Protectin (CD59) Antibody

abx139306-01mg 0.1 mg
EUR 444

Protectin (CD59) Antibody

abx139307-01mg 0.1 mg
EUR 427.2

Protectin (CD59) Antibody

20-abx111491
  • EUR 878.40
  • EUR 477.60
  • 150 ul
  • 50 ul

Protectin (CD59) Antibody

20-abx001417
  • EUR 493.20
  • EUR 710.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 50 ul

Protectin (CD59) Antibody

abx021467-100ug 100 ug
EUR 543.6

Protectin (CD59) Antibody

abx011952-100ug 100 ug
EUR 493.2

Protectin (CD59) Antibody

abx036096-100ug 100 ug
EUR 469.2

Protectin (CD59) Antibody

abx200391-100ug 100 ug
EUR 393.6

Protectin (CD59) Antibody

20-abx210170
  • EUR 526.80
  • EUR 393.60
  • 100 ug
  • 50 ug

Protectin (CD59) Antibody

20-abx210424
  • EUR 493.20
  • EUR 360.00
  • 100 ul
  • 50 ul

Protectin (CD59) Antibody

20-abx225094
  • EUR 444.00
  • EUR 727.20
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 50 ul

Protectin (CD59) Antibody

abx231489-100ug 100 ug
EUR 577.2

Protectin (CD59) Antibody

20-abx339758
  • EUR 493.20
  • EUR 360.00
  • 100 ul
  • 50 ul

Protectin (CD59) Antibody

20-abx270064
  • EUR 560.40
  • EUR 644.40
  • EUR 326.40
  • EUR 978.00
  • EUR 427.20
  • 100 tests
  • 200 tests
  • 25 tests
  • 500 tests
  • 50 tests

Protectin (CD59) Antibody

20-abx323672
  • EUR 376.80
  • EUR 292.80
  • 100 ug
  • 50 ug

Protectin (CD59) Antibody

20-abx178138
  • EUR 510.00
  • EUR 159.60
  • EUR 1412.40
  • EUR 693.60
  • EUR 393.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Protectin (CD59) Monoclonal Antibody (Rabbit), APC

4-MAB336Rb21-APC
  • EUR 422.40
  • EUR 4059.60
  • EUR 1126.80
  • EUR 540.00
  • EUR 267.60
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Rabbit Protectin (CD59). This antibody is labeled with APC.

Protectin (CD59) Monoclonal Antibody (Rabbit), Biotinylated

4-MAB336Rb21-Biotin
  • EUR 379.20
  • EUR 3046.80
  • EUR 896.40
  • EUR 465.60
  • EUR 265.20
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Rabbit Protectin (CD59). This antibody is labeled with Biotin.

Protectin (CD59) Monoclonal Antibody (Rabbit), Cy3

4-MAB336Rb21-Cy3
  • EUR 513.60
  • EUR 5362.80
  • EUR 1453.20
  • EUR 670.80
  • EUR 306.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Rabbit Protectin (CD59). This antibody is labeled with Cy3.

Protectin (CD59) Monoclonal Antibody (Rabbit), FITC

4-MAB336Rb21-FITC
  • EUR 362.40
  • EUR 3271.20
  • EUR 925.20
  • EUR 456.00
  • EUR 237.60
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Rabbit Protectin (CD59). This antibody is labeled with FITC.

Protectin (CD59) Monoclonal Antibody (Rabbit), HRP

4-MAB336Rb21-HRP
  • EUR 386.40
  • EUR 3537.60
  • EUR 996.00
  • EUR 488.40
  • EUR 252.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Rabbit Protectin (CD59). This antibody is labeled with HRP.

Protectin (CD59) Monoclonal Antibody (Rabbit), PE

4-MAB336Rb21-PE
  • EUR 362.40
  • EUR 3271.20
  • EUR 925.20
  • EUR 456.00
  • EUR 237.60
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Rabbit Protectin (CD59). This antibody is labeled with PE.

Anti-CD59 / Complement Regulatory Protein / Protectin Monoclonal Antibody

M00914 100ug/vial
EUR 476.4
Description: Mouse Monoclonal CD59 / Complement Regulatory Protein / Protectin Antibody. Validated in IF, IHC and tested in Human.

Mouse Protectin (CD59) Protein

20-abx068726
  • EUR 710.40
  • EUR 309.60
  • EUR 2131.20
  • EUR 844.80
  • EUR 526.80
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Protectin (CD59) Polyclonal Antibody (Mouse)

4-PAB336Mu01
  • EUR 291.60
  • EUR 2948.40
  • EUR 735.60
  • EUR 366.00
  • EUR 254.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Protectin (CD59)

Protectin (CD59) Monoclonal Antibody (Rabbit), APC-Cy7

4-MAB336Rb21-APC-Cy7
  • EUR 702.00
  • EUR 7975.20
  • EUR 2110.80
  • EUR 937.20
  • EUR 391.20
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Rabbit Protectin (CD59). This antibody is labeled with APC-Cy7.

Recombinant Protectin (CD59)

4-RPB336Hu01
  • EUR 539.33
  • EUR 267.60
  • EUR 1692.48
  • EUR 644.16
  • EUR 1168.32
  • EUR 436.80
  • EUR 4051.20
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Protectin expressed in: E.coli

Recombinant Protectin (CD59)

4-RPB336Mu01
  • EUR 507.07
  • EUR 259.20
  • EUR 1571.52
  • EUR 603.84
  • EUR 1087.68
  • EUR 415.20
  • EUR 3748.80
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Mouse Protectin expressed in: E.coli

Recombinant Protectin (CD59)

4-RPB336Po01
  • EUR 636.10
  • EUR 294.00
  • EUR 2055.36
  • EUR 765.12
  • EUR 1410.24
  • EUR 501.60
  • EUR 4958.40
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Pig Protectin expressed in: E.coli

Recombinant Protectin (CD59)

4-RPB336Ra01
  • EUR 496.32
  • EUR 256.80
  • EUR 1531.20
  • EUR 590.40
  • EUR 1060.80
  • EUR 408.00
  • EUR 3648.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Rat Protectin expressed in: E.coli

Recombinant Protectin (CD59)

4-RPB336Rb01
  • EUR 496.32
  • EUR 256.80
  • EUR 1531.20
  • EUR 590.40
  • EUR 1060.80
  • EUR 408.00
  • EUR 3648.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Rabbit Protectin expressed in: E.coli

Recombinant Protectin (CD59)

4-RPB336Si01
  • EUR 605.99
  • EUR 285.60
  • EUR 1942.46
  • EUR 727.49
  • EUR 1334.98
  • EUR 481.20
  • EUR 4676.16
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Simian Protectin expressed in: E.coli

Protectin (CD59) Antibody (HRP)

20-abx108081
  • EUR 493.20
  • EUR 2214.00