HER2 ātras internalizācijas un novirzītas cilvēku tirdzniecības molekulārais mehānisms, ko izraisa anti-HER2 biparatopiskais antiviela
HER2 (cilvēka epidermas attīstības problēmas 2. receptora), ErbB2 receptoru tirozīna kināzes, pastiprināšanās un pārmērīga ekspresija ir saistīta ar lielāko daļu cilvēku vēža un metastāžu. Ir ziņots, ka bispecifiska četrvērtīga anti-HER2 antiviela (anti-HER2-Bs), kas koncentrējas uz diviem HER2 nepilējošiem epitopiem IV zonā (trastuzumabs) un II zonā (39S), izraisa ātru HER2 internalizāciju un videi draudzīgu degradāciju. receptori.
Šajā pētījumā mēs izpētījām šīs antivielu izraisītās ātrās HER2 internalizācijas un intracelulārās tirdzniecības molekulāro mehānismu. Izmantojot kvantitatīvo fluorescējošo attēlveidošanu, mēs pretstatām anti-HER2-B un tā vecāku roku antivielu internalizācijas kinētikai atsevišķi vai maisījumos un daudzos internalizāciju veicinošos apstākļos. Rezultāti parādīja, ka ātrai anti-HER2-B internalizācijai izšķiroša nozīme bija vienlaicīgai katra epitopa iesaistei.
Anti-HER2-B un vecāku roku antivielu mobilā uzņemšana notika no klatrīna atkarīgas endocitozes veidā; tomēr antivielas šūnās satur pilnīgi atšķirīgus cilvēku tirdzniecības ceļus. Trastuzumabs 2 stundu laikā disociējās no HER2, ļaujot receptoriem atkārtoti pārstrādāt, savukārt anti-HER2-B palika saistīti ar receptoru visā endocītiskajā ceļā, pārdodot receptoru ubikvitināciju, tirdzniecību ar lizosomām un videi draudzīgu noārdīšanos.
Atbilstoši HER2 novirzīšanai uz degradāciju, anti-HER2-B ievērojami samazināja HER2 izdalīšanos un mainīja tā eksosomālo eksportu . Kopā šie rezultāti ļauj labāk izprast anti-Her2-B kustības mehānismu un var sniegt informāciju par racionālu anti-HER2 terapijas dizainu papildus dažādām bispecifiskām molekulām.
Cilvēkiem ar receptoru saistošās domēna specifiskās neitralizējošās monoklonālās antivielas pretstatā SARS-CoV un SARS-CoV-2
Ārkārtējā akūtā elpošanas sindroma (SARS) un 2019. gada koronavīrusa slimības (COVID-19) uzliesmojumi, ko izraisīja attiecīgi SARS-CoV un SARS-CoV-2, ir ārkārtīgi apdraudējuši pasaules sabiedrības labklājību un ekonomisko sistēmu. Šo vīrusu slimību terapija un profilakse ir cilvēka neitralizējošo monoklonālo antivielu (NMAbs) analīze un augšana.
Zinātnieki ir skrīnējuši neitralizējošās antivielas, kā antigēnu izmantojot vīrusa receptoru saistošo zonu (RBD), norādot, ka RBD ir iekļauti vairāki konformācijas neitralizējoši epitopi, kas ir galvenie strukturālie domēni neitralizējošo antivielu un T-šūnu imūnreakciju inducēšanai. Šajā novērtējumā ir apkopota RBD un RBD specifisko NMAb konstrukcija un veiktspēja, pretstatā SARS-CoV un SARS-CoV-2 pašlaik zem izaugsmes.
bernsklepo
Interleukin 8 (IL8) Monoclonal Antibody (Pig)
4-MAA080Po22
Cloud-Clone
EUR 298.80
EUR 3058.80
EUR 760.80
EUR 375.60
EUR 258.00
100ul 10ml 1ml 200ul 20ul
Description: A Mouse monoclonal antibody against Pig Interleukin 8 (IL8)
Interleukin 8 (IL8) Monoclonal Antibody (Pig)
4-MAA080Po24
Cloud-Clone
EUR 298.80
EUR 3058.80
EUR 760.80
EUR 375.60
EUR 258.00
100ul 10ml 1ml 200ul 20ul
Description: A Mouse monoclonal antibody against Pig Interleukin 8 (IL8)
Interleukin 8 (IL8) Monoclonal Antibody (Pig)
4-MAA080Po26
Cloud-Clone
EUR 298.80
EUR 3058.80
EUR 760.80
EUR 375.60
EUR 258.00
100ul 10ml 1ml 200ul 20ul
Description: A Mouse monoclonal antibody against Pig Interleukin 8 (IL8)
Interleukin 8 (IL8) Monoclonal Antibody (Horse)
4-MAA080Eq21
Cloud-Clone
EUR 325.20
EUR 3470.40
EUR 854.40
EUR 412.80
EUR 268.80
100ul 10ml 1ml 200ul 20ul
Description: A Mouse monoclonal antibody against Horse Interleukin 8 (IL8)
Interleukin 8 (IL8) Monoclonal Antibody (Human)
4-MAA080Hu22
Cloud-Clone
EUR 265.20
EUR 2536.80
EUR 642.00
EUR 328.80
EUR 243.60
100ul 10ml 1ml 200ul 20ul
Description: A Mouse monoclonal antibody against Human Interleukin 8 (IL8)
Interleukin 8 (IL8) Monoclonal Antibody (Human)
4-MAA080Hu24
Cloud-Clone
EUR 265.20
EUR 2536.80
EUR 642.00
EUR 328.80
EUR 243.60
100ul 10ml 1ml 200ul 20ul
Description: A Mouse monoclonal antibody against Human Interleukin 8 (IL8)
Interleukin 8 (IL8) Monoclonal Antibody (Rabbit)
4-MAA080Rb22
Cloud-Clone
EUR 301.20
EUR 3106.80
EUR 771.60
EUR 380.40
EUR 259.20
100ul 10ml 1ml 200ul 20ul
Description: A Mouse monoclonal antibody against Rabbit Interleukin 8 (IL8)
Interleukin 8 (IL8) Monoclonal Antibody (Chicken)
4-MAA080Ga22
Cloud-Clone
EUR 283.20
EUR 2805.60
EUR 703.20
EUR 352.80
EUR 250.80
100ul 10ml 1ml 200ul 20ul
Description: A Mouse monoclonal antibody against Chicken Interleukin 8 (IL8)
Interleukin 8 (IL8) Monoclonal Antibody (Pig), PE
4-MAA080Po22-PE
Cloud-Clone
EUR 358.80
EUR 3219.60
EUR 912.00
EUR 451.20
EUR 236.40
100ul 10ml 1ml 200ul 20ul
Description: A Mouse monoclonal antibody against Pig Interleukin 8 (IL8). This antibody is labeled with PE.
Interleukin 8 (IL8) Monoclonal Antibody (Pig), PE
4-MAA080Po24-PE
Cloud-Clone
EUR 358.80
EUR 3219.60
EUR 912.00
EUR 451.20
EUR 236.40
100ul 10ml 1ml 200ul 20ul
Description: A Mouse monoclonal antibody against Pig Interleukin 8 (IL8). This antibody is labeled with PE.
Interleukin 8 (IL8) Monoclonal Antibody (Pig), PE
4-MAA080Po26-PE
Cloud-Clone
EUR 358.80
EUR 3219.60
EUR 912.00
EUR 451.20
EUR 236.40
100ul 10ml 1ml 200ul 20ul
Description: A Mouse monoclonal antibody against Pig Interleukin 8 (IL8). This antibody is labeled with PE.
Interleukin 8 (IL8) Monoclonal Antibody (Pig), APC
4-MAA080Po22-APC
Cloud-Clone
EUR 418.80
EUR 3994.80
EUR 1111.20
EUR 534.00
EUR 265.20
100ul 10ml 1ml 200ul 20ul
Description: A Mouse monoclonal antibody against Pig Interleukin 8 (IL8). This antibody is labeled with APC.
Interleukin 8 (IL8) Monoclonal Antibody (Pig), Cy3
4-MAA080Po22-Cy3
Cloud-Clone
EUR 507.60
EUR 5276.40
EUR 1431.60
EUR 662.40
EUR 303.60
100ul 10ml 1ml 200ul 20ul
Description: A Mouse monoclonal antibody against Pig Interleukin 8 (IL8). This antibody is labeled with Cy3.
Interleukin 8 (IL8) Monoclonal Antibody (Pig), HRP
4-MAA080Po22-HRP
Cloud-Clone
EUR 382.80
EUR 3481.20
EUR 982.80
EUR 482.40
EUR 249.60
100ul 10ml 1ml 200ul 20ul
Description: A Mouse monoclonal antibody against Pig Interleukin 8 (IL8). This antibody is labeled with HRP.
Interleukin 8 (IL8) Monoclonal Antibody (Pig), APC
4-MAA080Po24-APC
Cloud-Clone
EUR 418.80
EUR 3994.80
EUR 1111.20
EUR 534.00
EUR 265.20
100ul 10ml 1ml 200ul 20ul
Description: A Mouse monoclonal antibody against Pig Interleukin 8 (IL8). This antibody is labeled with APC.
Interleukin 8 (IL8) Monoclonal Antibody (Pig), Cy3
4-MAA080Po24-Cy3
Cloud-Clone
EUR 507.60
EUR 5276.40
EUR 1431.60
EUR 662.40
EUR 303.60
100ul 10ml 1ml 200ul 20ul
Description: A Mouse monoclonal antibody against Pig Interleukin 8 (IL8). This antibody is labeled with Cy3.
Interleukin 8 (IL8) Monoclonal Antibody (Pig), HRP
4-MAA080Po24-HRP
Cloud-Clone
EUR 382.80
EUR 3481.20
EUR 982.80
EUR 482.40
EUR 249.60
100ul 10ml 1ml 200ul 20ul
Description: A Mouse monoclonal antibody against Pig Interleukin 8 (IL8). This antibody is labeled with HRP.
Interleukin 8 (IL8) Monoclonal Antibody (Pig), APC
4-MAA080Po26-APC
Cloud-Clone
EUR 418.80
EUR 3994.80
EUR 1111.20
EUR 534.00
EUR 265.20
100ul 10ml 1ml 200ul 20ul
Description: A Mouse monoclonal antibody against Pig Interleukin 8 (IL8). This antibody is labeled with APC.
Interleukin 8 (IL8) Monoclonal Antibody (Pig), Cy3
4-MAA080Po26-Cy3
Cloud-Clone
EUR 507.60
EUR 5276.40
EUR 1431.60
EUR 662.40
EUR 303.60
100ul 10ml 1ml 200ul 20ul
Description: A Mouse monoclonal antibody against Pig Interleukin 8 (IL8). This antibody is labeled with Cy3.
Interleukin 8 (IL8) Monoclonal Antibody (Pig), HRP
4-MAA080Po26-HRP
Cloud-Clone
EUR 382.80
EUR 3481.20
EUR 982.80
EUR 482.40
EUR 249.60
100ul 10ml 1ml 200ul 20ul
Description: A Mouse monoclonal antibody against Pig Interleukin 8 (IL8). This antibody is labeled with HRP.
Interleukin 8 (IL8) Monoclonal Antibody (Horse), PE
4-MAA080Eq21-PE
Cloud-Clone
EUR 390.00
EUR 3668.40
EUR 1024.80
EUR 495.60
EUR 248.40
100ul 10ml 1ml 200ul 20ul
Description: A Mouse monoclonal antibody against Horse Interleukin 8 (IL8). This antibody is labeled with PE.
Interleukin 8 (IL8) Monoclonal Antibody (Human), PE
4-MAA080Hu22-PE
Cloud-Clone
EUR 319.20
EUR 2649.60
EUR 770.40
EUR 393.60
EUR 218.40
100ul 10ml 1ml 200ul 20ul
Description: A Mouse monoclonal antibody against Human Interleukin 8 (IL8). This antibody is labeled with PE.
Interleukin 8 (IL8) Monoclonal Antibody (Human), PE
4-MAA080Hu24-PE
Cloud-Clone
EUR 319.20
EUR 2649.60
EUR 770.40
EUR 393.60
EUR 218.40
100ul 10ml 1ml 200ul 20ul
Description: A Mouse monoclonal antibody against Human Interleukin 8 (IL8). This antibody is labeled with PE.
Interleukin 8 (IL8) Monoclonal Antibody (Pig), FITC
4-MAA080Po22-FITC
Cloud-Clone
EUR 358.80
EUR 3219.60
EUR 912.00
EUR 451.20
EUR 236.40
100ul 10ml 1ml 200ul 20ul
Description: A Mouse monoclonal antibody against Pig Interleukin 8 (IL8). This antibody is labeled with FITC.
Interleukin 8 (IL8) Monoclonal Antibody (Pig), FITC
4-MAA080Po24-FITC
Cloud-Clone
EUR 358.80
EUR 3219.60
EUR 912.00
EUR 451.20
EUR 236.40
100ul 10ml 1ml 200ul 20ul
Description: A Mouse monoclonal antibody against Pig Interleukin 8 (IL8). This antibody is labeled with FITC.
Interleukin 8 (IL8) Monoclonal Antibody (Pig), FITC
4-MAA080Po26-FITC
Cloud-Clone
EUR 358.80
EUR 3219.60
EUR 912.00
EUR 451.20
EUR 236.40
100ul 10ml 1ml 200ul 20ul
Description: A Mouse monoclonal antibody against Pig Interleukin 8 (IL8). This antibody is labeled with FITC.
Interleukin 8 (IL8) Monoclonal Antibody (Human, Dog)
4-MAA080Ca22
Cloud-Clone
EUR 265.20
EUR 2536.80
EUR 642.00
EUR 328.80
EUR 243.60
100ul 10ml 1ml 200ul 20ul
Description: A Mouse monoclonal antibody against Human, Dog Interleukin 8 (IL8)
Interleukin 8 (IL8) Monoclonal Antibody (Horse), APC
4-MAA080Eq21-APC
Cloud-Clone
EUR 458.40
EUR 4556.40
EUR 1251.60
EUR 590.40
EUR 280.80
100ul 10ml 1ml 200ul 20ul
Description: A Mouse monoclonal antibody against Horse Interleukin 8 (IL8). This antibody is labeled with APC.
Interleukin 8 (IL8) Monoclonal Antibody (Horse), Cy3
4-MAA080Eq21-Cy3
Cloud-Clone
EUR 561.60
EUR 6025.20
EUR 1618.80
EUR 736.80
EUR 325.20
100ul 10ml 1ml 200ul 20ul
Description: A Mouse monoclonal antibody against Horse Interleukin 8 (IL8). This antibody is labeled with Cy3.
Interleukin 8 (IL8) Monoclonal Antibody (Horse), HRP
4-MAA080Eq21-HRP
Cloud-Clone
EUR 417.60
EUR 3968.40
EUR 1104.00
EUR 531.60
EUR 264.00
100ul 10ml 1ml 200ul 20ul
Description: A Mouse monoclonal antibody against Horse Interleukin 8 (IL8). This antibody is labeled with HRP.
Interleukin 8 (IL8) Monoclonal Antibody (Human), APC
4-MAA080Hu22-APC
Cloud-Clone
EUR 368.40
EUR 3282.00
EUR 932.40
EUR 463.20
EUR 243.60
100ul 10ml 1ml 200ul 20ul
Description: A Mouse monoclonal antibody against Human Interleukin 8 (IL8). This antibody is labeled with APC.
Interleukin 8 (IL8) Monoclonal Antibody (Human), Cy3
4-MAA080Hu22-Cy3
Cloud-Clone
EUR 441.60
EUR 4326.00
EUR 1194.00
EUR 567.60
EUR 274.80
100ul 10ml 1ml 200ul 20ul
Description: A Mouse monoclonal antibody against Human Interleukin 8 (IL8). This antibody is labeled with Cy3.
Interleukin 8 (IL8) Monoclonal Antibody (Human), HRP
4-MAA080Hu22-HRP
Cloud-Clone
EUR 339.60
EUR 2864.40
EUR 828.00
EUR 421.20
EUR 230.40
100ul 10ml 1ml 200ul 20ul
Description: A Mouse monoclonal antibody against Human Interleukin 8 (IL8). This antibody is labeled with HRP.
Interleukin 8 (IL8) Monoclonal Antibody (Human), APC
4-MAA080Hu24-APC
Cloud-Clone
EUR 368.40
EUR 3282.00
EUR 932.40
EUR 463.20
EUR 243.60
100ul 10ml 1ml 200ul 20ul
Description: A Mouse monoclonal antibody against Human Interleukin 8 (IL8). This antibody is labeled with APC.
Interleukin 8 (IL8) Monoclonal Antibody (Human), Cy3
4-MAA080Hu24-Cy3
Cloud-Clone
EUR 441.60
EUR 4326.00
EUR 1194.00
EUR 567.60
EUR 274.80
100ul 10ml 1ml 200ul 20ul
Description: A Mouse monoclonal antibody against Human Interleukin 8 (IL8). This antibody is labeled with Cy3.
Interleukin 8 (IL8) Monoclonal Antibody (Human), HRP
4-MAA080Hu24-HRP
Cloud-Clone
EUR 339.60
EUR 2864.40
EUR 828.00
EUR 421.20
EUR 230.40
100ul 10ml 1ml 200ul 20ul
Description: A Mouse monoclonal antibody against Human Interleukin 8 (IL8). This antibody is labeled with HRP.
Interleukin 8 (IL8) Monoclonal Antibody (Rabbit), PE
4-MAA080Rb22-PE
Cloud-Clone
EUR 362.40
EUR 3271.20
EUR 925.20
EUR 456.00
EUR 237.60
100ul 10ml 1ml 200ul 20ul
Description: A Mouse monoclonal antibody against Rabbit Interleukin 8 (IL8). This antibody is labeled with PE.
Interleukin 8 (IL8) Monoclonal Antibody (Horse), FITC
4-MAA080Eq21-FITC
Cloud-Clone
EUR 390.00
EUR 3668.40
EUR 1024.80
EUR 495.60
EUR 248.40
100ul 10ml 1ml 200ul 20ul
Description: A Mouse monoclonal antibody against Horse Interleukin 8 (IL8). This antibody is labeled with FITC.
Interleukin 8 (IL8) Monoclonal Antibody (Chicken), PE
4-MAA080Ga22-PE
Cloud-Clone
EUR 339.60
EUR 2942.40
EUR 843.60
EUR 423.60
EUR 226.80
100ul 10ml 1ml 200ul 20ul
Description: A Mouse monoclonal antibody against Chicken Interleukin 8 (IL8). This antibody is labeled with PE.
Interleukin 8 (IL8) Monoclonal Antibody (Guinea pig)
4-MAA080Gu21
Cloud-Clone
EUR 310.80
EUR 3249.60
EUR 804.00
EUR 393.60
EUR 262.80
100ul 10ml 1ml 200ul 20ul
Description: A Mouse monoclonal antibody against Guinea pig Interleukin 8 (IL8)
Interleukin 8 (IL8) Monoclonal Antibody (Guinea pig)
4-MAA080Gu24
Cloud-Clone
EUR 310.80
EUR 3249.60
EUR 804.00
EUR 393.60
EUR 262.80
100ul 10ml 1ml 200ul 20ul
Description: A Mouse monoclonal antibody against Guinea pig Interleukin 8 (IL8)
Interleukin 8 (IL8) Monoclonal Antibody (Human), FITC
4-MAA080Hu22-FITC
Cloud-Clone
EUR 319.20
EUR 2649.60
EUR 770.40
EUR 393.60
EUR 218.40
100ul 10ml 1ml 200ul 20ul
Description: A Mouse monoclonal antibody against Human Interleukin 8 (IL8). This antibody is labeled with FITC.
Interleukin 8 (IL8) Monoclonal Antibody (Human), FITC
4-MAA080Hu24-FITC
Cloud-Clone
EUR 319.20
EUR 2649.60
EUR 770.40
EUR 393.60
EUR 218.40
100ul 10ml 1ml 200ul 20ul
Description: A Mouse monoclonal antibody against Human Interleukin 8 (IL8). This antibody is labeled with FITC.
Interleukin 8 (IL8) Monoclonal Antibody (Rabbit), APC
4-MAA080Rb22-APC
Cloud-Clone
EUR 422.40
EUR 4059.60
EUR 1126.80
EUR 540.00
EUR 267.60
100ul 10ml 1ml 200ul 20ul
Description: A Mouse monoclonal antibody against Rabbit Interleukin 8 (IL8). This antibody is labeled with APC.
Interleukin 8 (IL8) Monoclonal Antibody (Rabbit), Cy3
4-MAA080Rb22-Cy3
Cloud-Clone
EUR 513.60
EUR 5362.80
EUR 1453.20
EUR 670.80
EUR 306.00
100ul 10ml 1ml 200ul 20ul
Description: A Mouse monoclonal antibody against Rabbit Interleukin 8 (IL8). This antibody is labeled with Cy3.
Interleukin 8 (IL8) Monoclonal Antibody (Rabbit), HRP
4-MAA080Rb22-HRP
Cloud-Clone
EUR 386.40
EUR 3537.60
EUR 996.00
EUR 488.40
EUR 252.00
100ul 10ml 1ml 200ul 20ul
Description: A Mouse monoclonal antibody against Rabbit Interleukin 8 (IL8). This antibody is labeled with HRP.
Interleukin 8 (IL8) Monoclonal Antibody (Chicken), APC
4-MAA080Ga22-APC
Cloud-Clone
EUR 394.80
EUR 3649.20
EUR 1024.80
EUR 499.20
EUR 254.40
100ul 10ml 1ml 200ul 20ul
Description: A Mouse monoclonal antibody against Chicken Interleukin 8 (IL8). This antibody is labeled with APC.
Interleukin 8 (IL8) Monoclonal Antibody (Chicken), Cy3
4-MAA080Ga22-Cy3
Cloud-Clone
EUR 476.40
EUR 4815.60
EUR 1316.40
EUR 615.60
EUR 289.20
100ul 10ml 1ml 200ul 20ul
Description: A Mouse monoclonal antibody against Chicken Interleukin 8 (IL8). This antibody is labeled with Cy3.
Interleukin 8 (IL8) Monoclonal Antibody (Chicken), HRP
4-MAA080Ga22-HRP
Cloud-Clone
EUR 362.40
EUR 3182.40
EUR 907.20
EUR 452.40
EUR 240.00
100ul 10ml 1ml 200ul 20ul
Description: A Mouse monoclonal antibody against Chicken Interleukin 8 (IL8). This antibody is labeled with HRP.
Interleukin 8 (IL8) Monoclonal Antibody (Rabbit), FITC
4-MAA080Rb22-FITC
Cloud-Clone
EUR 362.40
EUR 3271.20
EUR 925.20
EUR 456.00
EUR 237.60
100ul 10ml 1ml 200ul 20ul
Description: A Mouse monoclonal antibody against Rabbit Interleukin 8 (IL8). This antibody is labeled with FITC.
Interleukin 8 (IL8) Monoclonal Antibody (Chicken), FITC
4-MAA080Ga22-FITC
Cloud-Clone
EUR 339.60
EUR 2942.40
EUR 843.60
EUR 423.60
EUR 226.80
100ul 10ml 1ml 200ul 20ul
Description: A Mouse monoclonal antibody against Chicken Interleukin 8 (IL8). This antibody is labeled with FITC.
Interleukin 8 (IL8) Monoclonal Antibody (Rhesus monkey)
4-MAA080Si21
Cloud-Clone
EUR 310.80
EUR 3249.60
EUR 804.00
EUR 393.60
EUR 262.80
100ul 10ml 1ml 200ul 20ul
Description: A Mouse monoclonal antibody against Rhesus monkey Interleukin 8 (IL8)
Interleukin 8 (IL8) Monoclonal Antibody (Rhesus monkey)
4-MAA080Si22
Cloud-Clone
EUR 310.80
EUR 3249.60
EUR 804.00
EUR 393.60
EUR 262.80
100ul 10ml 1ml 200ul 20ul
Description: A Mouse monoclonal antibody against Rhesus monkey Interleukin 8 (IL8)
Interleukin 8 (IL8) Monoclonal Antibody (Human, Dog), PE
4-MAA080Ca22-PE
Cloud-Clone
EUR 319.20
EUR 2649.60
EUR 770.40
EUR 393.60
EUR 218.40
100ul 10ml 1ml 200ul 20ul
Description: A Mouse monoclonal antibody against Human, Dog Interleukin 8 (IL8). This antibody is labeled with PE.
Interleukin 8 (IL8) Monoclonal Antibody (Pig), Biotinylated
4-MAA080Po22-Biotin
Cloud-Clone
EUR 376.80
EUR 2998.80
EUR 884.40
EUR 460.80
EUR 264.00
100ul 10ml 1ml 200ul 20ul
Description: A Mouse monoclonal antibody against Pig Interleukin 8 (IL8). This antibody is labeled with Biotin.
Interleukin 8 (IL8) Monoclonal Antibody (Pig), Biotinylated
4-MAA080Po24-Biotin
Cloud-Clone
EUR 376.80
EUR 2998.80
EUR 884.40
EUR 460.80
EUR 264.00
100ul 10ml 1ml 200ul 20ul
Description: A Mouse monoclonal antibody against Pig Interleukin 8 (IL8). This antibody is labeled with Biotin.
Interleukin 8 (IL8) Monoclonal Antibody (Pig), Biotinylated
4-MAA080Po26-Biotin
Cloud-Clone
EUR 376.80
EUR 2998.80
EUR 884.40
EUR 460.80
EUR 264.00
100ul 10ml 1ml 200ul 20ul
Description: A Mouse monoclonal antibody against Pig Interleukin 8 (IL8). This antibody is labeled with Biotin.
Interleukin 8 (IL8) Monoclonal Antibody (Human, Dog), APC
4-MAA080Ca22-APC
Cloud-Clone
EUR 368.40
EUR 3282.00
EUR 932.40
EUR 463.20
EUR 243.60
100ul 10ml 1ml 200ul 20ul
Description: A Mouse monoclonal antibody against Human, Dog Interleukin 8 (IL8). This antibody is labeled with APC.
Interleukin 8 (IL8) Monoclonal Antibody (Human, Dog), Cy3
4-MAA080Ca22-Cy3
Cloud-Clone
EUR 441.60
EUR 4326.00
EUR 1194.00
EUR 567.60
EUR 274.80
100ul 10ml 1ml 200ul 20ul
Description: A Mouse monoclonal antibody against Human, Dog Interleukin 8 (IL8). This antibody is labeled with Cy3.
Interleukin 8 (IL8) Monoclonal Antibody (Human, Dog), HRP
4-MAA080Ca22-HRP
Cloud-Clone
EUR 339.60
EUR 2864.40
EUR 828.00
EUR 421.20
EUR 230.40
100ul 10ml 1ml 200ul 20ul
Description: A Mouse monoclonal antibody against Human, Dog Interleukin 8 (IL8). This antibody is labeled with HRP.
Interleukin 8 (IL8) Monoclonal Antibody (Guinea pig), PE
4-MAA080Gu21-PE
Cloud-Clone
EUR 373.20
EUR 3427.20
EUR 964.80
EUR 471.60
EUR 242.40
100ul 10ml 1ml 200ul 20ul
Description: A Mouse monoclonal antibody against Guinea pig Interleukin 8 (IL8). This antibody is labeled with PE.
Interleukin 8 (IL8) Monoclonal Antibody (Guinea pig), PE
4-MAA080Gu24-PE
Cloud-Clone
EUR 373.20
EUR 3427.20
EUR 964.80
EUR 471.60
EUR 242.40
100ul 10ml 1ml 200ul 20ul
Description: A Mouse monoclonal antibody against Guinea pig Interleukin 8 (IL8). This antibody is labeled with PE.
Interleukin 8 (IL8) Monoclonal Antibody (Pig), APC-Cy7
4-MAA080Po22-APC-Cy7
Cloud-Clone
EUR 693.60
EUR 7845.60
EUR 2078.40
EUR 924.00
EUR 386.40
100ul 10ml 1ml 200ul 20ul
Description: A Mouse monoclonal antibody against Pig Interleukin 8 (IL8). This antibody is labeled with APC-Cy7.
Interleukin 8 (IL8) Monoclonal Antibody (Pig), APC-Cy7
4-MAA080Po24-APC-Cy7
Cloud-Clone
EUR 693.60
EUR 7845.60
EUR 2078.40
EUR 924.00
EUR 386.40
100ul 10ml 1ml 200ul 20ul
Description: A Mouse monoclonal antibody against Pig Interleukin 8 (IL8). This antibody is labeled with APC-Cy7.
Interleukin 8 (IL8) Monoclonal Antibody (Pig), APC-Cy7
4-MAA080Po26-APC-Cy7
Cloud-Clone
EUR 693.60
EUR 7845.60
EUR 2078.40
EUR 924.00
EUR 386.40
100ul 10ml 1ml 200ul 20ul
Description: A Mouse monoclonal antibody against Pig Interleukin 8 (IL8). This antibody is labeled with APC-Cy7.
Interleukin 8 (IL8) Monoclonal Antibody (Human, Dog), FITC
4-MAA080Ca22-FITC
Cloud-Clone
EUR 319.20
EUR 2649.60
EUR 770.40
EUR 393.60
EUR 218.40
100ul 10ml 1ml 200ul 20ul
Description: A Mouse monoclonal antibody against Human, Dog Interleukin 8 (IL8). This antibody is labeled with FITC.
Interleukin 8 (IL8) Monoclonal Antibody (Guinea pig), APC
4-MAA080Gu21-APC
Cloud-Clone
EUR 436.80
EUR 4254.00
EUR 1176.00
EUR 560.40
EUR 272.40
100ul 10ml 1ml 200ul 20ul
Description: A Mouse monoclonal antibody against Guinea pig Interleukin 8 (IL8). This antibody is labeled with APC.
Interleukin 8 (IL8) Monoclonal Antibody (Guinea pig), Cy3
4-MAA080Gu21-Cy3
Cloud-Clone
EUR 532.80
EUR 5622.00
EUR 1518.00
EUR 697.20
EUR 313.20
100ul 10ml 1ml 200ul 20ul
Description: A Mouse monoclonal antibody against Guinea pig Interleukin 8 (IL8). This antibody is labeled with Cy3.
Interleukin 8 (IL8) Monoclonal Antibody (Guinea pig), HRP
4-MAA080Gu21-HRP
Cloud-Clone
EUR 398.40
EUR 3706.80
EUR 1039.20
EUR 505.20
EUR 255.60
100ul 10ml 1ml 200ul 20ul
Description: A Mouse monoclonal antibody against Guinea pig Interleukin 8 (IL8). This antibody is labeled with HRP.
Interleukin 8 (IL8) Monoclonal Antibody (Guinea pig), APC
4-MAA080Gu24-APC
Cloud-Clone
EUR 436.80
EUR 4254.00
EUR 1176.00
EUR 560.40
EUR 272.40
100ul 10ml 1ml 200ul 20ul
Description: A Mouse monoclonal antibody against Guinea pig Interleukin 8 (IL8). This antibody is labeled with APC.
Interleukin 8 (IL8) Monoclonal Antibody (Guinea pig), Cy3
4-MAA080Gu24-Cy3
Cloud-Clone
EUR 532.80
EUR 5622.00
EUR 1518.00
EUR 697.20
EUR 313.20
100ul 10ml 1ml 200ul 20ul
Description: A Mouse monoclonal antibody against Guinea pig Interleukin 8 (IL8). This antibody is labeled with Cy3.
Interleukin 8 (IL8) Monoclonal Antibody (Guinea pig), HRP
4-MAA080Gu24-HRP
Cloud-Clone
EUR 398.40
EUR 3706.80
EUR 1039.20
EUR 505.20
EUR 255.60
100ul 10ml 1ml 200ul 20ul
Description: A Mouse monoclonal antibody against Guinea pig Interleukin 8 (IL8). This antibody is labeled with HRP.
Interleukin 8 (IL8) Monoclonal Antibody (Horse), Biotinylated
4-MAA080Eq21-Biotin
Cloud-Clone
EUR 405.60
EUR 3410.40
EUR 987.60
EUR 502.80
EUR 276.00
100ul 10ml 1ml 200ul 20ul
Description: A Mouse monoclonal antibody against Horse Interleukin 8 (IL8). This antibody is labeled with Biotin.
Interleukin 8 (IL8) Monoclonal Antibody (Human), Biotinylated
4-MAA080Hu22-Biotin
Cloud-Clone
EUR 339.60
EUR 2476.80
EUR 753.60
EUR 409.20
EUR 248.40
100ul 10ml 1ml 200ul 20ul
Description: A Mouse monoclonal antibody against Human Interleukin 8 (IL8). This antibody is labeled with Biotin.
Interleukin 8 (IL8) Monoclonal Antibody (Human), Biotinylated
4-MAA080Hu24-Biotin
Cloud-Clone
EUR 339.60
EUR 2476.80
EUR 753.60
EUR 409.20
EUR 248.40
100ul 10ml 1ml 200ul 20ul
Description: A Mouse monoclonal antibody against Human Interleukin 8 (IL8). This antibody is labeled with Biotin.
Interleukin 8 (IL8) Monoclonal Antibody (Horse), APC-Cy7
4-MAA080Eq21-APC-Cy7
Cloud-Clone
EUR 772.80
EUR 8968.80
EUR 2359.20
EUR 1036.80
EUR 418.80
100ul 10ml 1ml 200ul 20ul
Description: A Mouse monoclonal antibody against Horse Interleukin 8 (IL8). This antibody is labeled with APC-Cy7.
Interleukin 8 (IL8) Monoclonal Antibody (Guinea pig), FITC
4-MAA080Gu21-FITC
Cloud-Clone
EUR 373.20
EUR 3427.20
EUR 964.80
EUR 471.60
EUR 242.40
100ul 10ml 1ml 200ul 20ul
Description: A Mouse monoclonal antibody against Guinea pig Interleukin 8 (IL8). This antibody is labeled with FITC.
Interleukin 8 (IL8) Monoclonal Antibody (Guinea pig), FITC
4-MAA080Gu24-FITC
Cloud-Clone
EUR 373.20
EUR 3427.20
EUR 964.80
EUR 471.60
EUR 242.40
100ul 10ml 1ml 200ul 20ul
Description: A Mouse monoclonal antibody against Guinea pig Interleukin 8 (IL8). This antibody is labeled with FITC.
Interleukin 8 (IL8) Monoclonal Antibody (Human), APC-Cy7
4-MAA080Hu22-APC-Cy7
Cloud-Clone
EUR 594.00
EUR 6420.00
EUR 1722.00
EUR 782.40
EUR 343.20
100ul 10ml 1ml 200ul 20ul
Description: A Mouse monoclonal antibody against Human Interleukin 8 (IL8). This antibody is labeled with APC-Cy7.
Interleukin 8 (IL8) Monoclonal Antibody (Human), APC-Cy7
4-MAA080Hu24-APC-Cy7
Cloud-Clone
EUR 594.00
EUR 6420.00
EUR 1722.00
EUR 782.40
EUR 343.20
100ul 10ml 1ml 200ul 20ul
Description: A Mouse monoclonal antibody against Human Interleukin 8 (IL8). This antibody is labeled with APC-Cy7.
Interleukin 8 (IL8) Monoclonal Antibody (Rabbit), Biotinylated
4-MAA080Rb22-Biotin
Cloud-Clone
EUR 379.20
EUR 3046.80
EUR 896.40
EUR 465.60
EUR 265.20
100ul 10ml 1ml 200ul 20ul
Description: A Mouse monoclonal antibody against Rabbit Interleukin 8 (IL8). This antibody is labeled with Biotin.
Interleukin 8 (IL8) Monoclonal Antibody (Rhesus monkey), PE
4-MAA080Si21-PE
Cloud-Clone
EUR 373.20
EUR 3427.20
EUR 964.80
EUR 471.60
EUR 242.40
100ul 10ml 1ml 200ul 20ul
Description: A Mouse monoclonal antibody against Rhesus monkey Interleukin 8 (IL8). This antibody is labeled with PE.
Interleukin 8 (IL8) Monoclonal Antibody (Rhesus monkey), PE
4-MAA080Si22-PE
Cloud-Clone
EUR 373.20
EUR 3427.20
EUR 964.80
EUR 471.60
EUR 242.40
100ul 10ml 1ml 200ul 20ul
Description: A Mouse monoclonal antibody against Rhesus monkey Interleukin 8 (IL8). This antibody is labeled with PE.
Interleukin 8 (IL8) Monoclonal Antibody (Rabbit), APC-Cy7
4-MAA080Rb22-APC-Cy7
Cloud-Clone
EUR 702.00
EUR 7975.20
EUR 2110.80
EUR 937.20
EUR 391.20
100ul 10ml 1ml 200ul 20ul
Description: A Mouse monoclonal antibody against Rabbit Interleukin 8 (IL8). This antibody is labeled with APC-Cy7.
Interleukin 8 (IL8) Monoclonal Antibody (Chicken), Biotinylated
4-MAA080Ga22-Biotin
Cloud-Clone
EUR 358.80
EUR 2745.60
EUR 820.80
EUR 435.60
EUR 256.80
100ul 10ml 1ml 200ul 20ul
Description: A Mouse monoclonal antibody against Chicken Interleukin 8 (IL8). This antibody is labeled with Biotin.
Interleukin 8 (IL8) Monoclonal Antibody (Rhesus monkey), APC
4-MAA080Si21-APC
Cloud-Clone
EUR 436.80
EUR 4254.00
EUR 1176.00
EUR 560.40
EUR 272.40
100ul 10ml 1ml 200ul 20ul
Description: A Mouse monoclonal antibody against Rhesus monkey Interleukin 8 (IL8). This antibody is labeled with APC.
Interleukin 8 (IL8) Monoclonal Antibody (Rhesus monkey), Cy3
4-MAA080Si21-Cy3
Cloud-Clone
EUR 532.80
EUR 5622.00
EUR 1518.00
EUR 697.20
EUR 313.20
100ul 10ml 1ml 200ul 20ul
Description: A Mouse monoclonal antibody against Rhesus monkey Interleukin 8 (IL8). This antibody is labeled with Cy3.
Interleukin 8 (IL8) Monoclonal Antibody (Rhesus monkey), HRP
4-MAA080Si21-HRP
Cloud-Clone
EUR 398.40
EUR 3706.80
EUR 1039.20
EUR 505.20
EUR 255.60
100ul 10ml 1ml 200ul 20ul
Description: A Mouse monoclonal antibody against Rhesus monkey Interleukin 8 (IL8). This antibody is labeled with HRP.
Interleukin 8 (IL8) Monoclonal Antibody (Rhesus monkey), APC
4-MAA080Si22-APC
Cloud-Clone
EUR 436.80
EUR 4254.00
EUR 1176.00
EUR 560.40
EUR 272.40
100ul 10ml 1ml 200ul 20ul
Description: A Mouse monoclonal antibody against Rhesus monkey Interleukin 8 (IL8). This antibody is labeled with APC.
Interleukin 8 (IL8) Monoclonal Antibody (Rhesus monkey), Cy3
4-MAA080Si22-Cy3
Cloud-Clone
EUR 532.80
EUR 5622.00
EUR 1518.00
EUR 697.20
EUR 313.20
100ul 10ml 1ml 200ul 20ul
Description: A Mouse monoclonal antibody against Rhesus monkey Interleukin 8 (IL8). This antibody is labeled with Cy3.
Interleukin 8 (IL8) Monoclonal Antibody (Rhesus monkey), HRP
4-MAA080Si22-HRP
Cloud-Clone
EUR 398.40
EUR 3706.80
EUR 1039.20
EUR 505.20
EUR 255.60
100ul 10ml 1ml 200ul 20ul
Description: A Mouse monoclonal antibody against Rhesus monkey Interleukin 8 (IL8). This antibody is labeled with HRP.
Interleukin 8 (IL8) Monoclonal Antibody (Chicken), APC-Cy7
4-MAA080Ga22-APC-Cy7
Cloud-Clone
EUR 645.60
EUR 7154.40
EUR 1905.60
EUR 855.60
EUR 364.80
100ul 10ml 1ml 200ul 20ul
Description: A Mouse monoclonal antibody against Chicken Interleukin 8 (IL8). This antibody is labeled with APC-Cy7.
Interleukin 8 (IL8) Monoclonal Antibody (Rhesus monkey), FITC
4-MAA080Si21-FITC
Cloud-Clone
EUR 373.20
EUR 3427.20
EUR 964.80
EUR 471.60
EUR 242.40
100ul 10ml 1ml 200ul 20ul
Description: A Mouse monoclonal antibody against Rhesus monkey Interleukin 8 (IL8). This antibody is labeled with FITC.
Interleukin 8 (IL8) Monoclonal Antibody (Rhesus monkey), FITC
4-MAA080Si22-FITC
Cloud-Clone
EUR 373.20
EUR 3427.20
EUR 964.80
EUR 471.60
EUR 242.40
100ul 10ml 1ml 200ul 20ul
Description: A Mouse monoclonal antibody against Rhesus monkey Interleukin 8 (IL8). This antibody is labeled with FITC.
Mouse Anti Sheep Interleukin-8 Monoclonal Antibody
CABT-48526MS
Creative Diagnostics
0.25 mg
EUR 1070.4
Interleukin 8 (IL8) Monoclonal Antibody (Human, Dog), APC-Cy7
4-MAA080Ca22-APC-Cy7
Cloud-Clone
EUR 594.00
EUR 6420.00
EUR 1722.00
EUR 782.40
EUR 343.20
100ul 10ml 1ml 200ul 20ul
Description: A Mouse monoclonal antibody against Human, Dog Interleukin 8 (IL8). This antibody is labeled with APC-Cy7.
Interleukin 8 (IL8) Monoclonal Antibody (Human, Dog), Biotinylated
4-MAA080Ca22-Biotin
Cloud-Clone
EUR 339.60
EUR 2476.80
EUR 753.60
EUR 409.20
EUR 248.40
100ul 10ml 1ml 200ul 20ul
Description: A Mouse monoclonal antibody against Human, Dog Interleukin 8 (IL8). This antibody is labeled with Biotin.
Interleukin 8 (IL8) Monoclonal Antibody (Guinea pig), APC-Cy7
4-MAA080Gu21-APC-Cy7
Cloud-Clone
EUR 729.60
EUR 8364.00
EUR 2208.00
EUR 976.80
EUR 402.00
100ul 10ml 1ml 200ul 20ul
Description: A Mouse monoclonal antibody against Guinea pig Interleukin 8 (IL8). This antibody is labeled with APC-Cy7.
Interleukin 8 (IL8) Monoclonal Antibody (Guinea pig), APC-Cy7
4-MAA080Gu24-APC-Cy7
Cloud-Clone
EUR 729.60
EUR 8364.00
EUR 2208.00
EUR 976.80
EUR 402.00
100ul 10ml 1ml 200ul 20ul
Description: A Mouse monoclonal antibody against Guinea pig Interleukin 8 (IL8). This antibody is labeled with APC-Cy7.
Interleukin 8 (IL8) Monoclonal Antibody (Guinea pig), Biotinylated
4-MAA080Gu21-Biotin
Cloud-Clone
EUR 390.00
EUR 3189.60
EUR 932.40
EUR 480.00
EUR 270.00
100ul 10ml 1ml 200ul 20ul
Description: A Mouse monoclonal antibody against Guinea pig Interleukin 8 (IL8). This antibody is labeled with Biotin.
Interleukin 8 (IL8) Monoclonal Antibody (Guinea pig), Biotinylated
4-MAA080Gu24-Biotin
Cloud-Clone
EUR 390.00
EUR 3189.60
EUR 932.40
EUR 480.00
EUR 270.00
100ul 10ml 1ml 200ul 20ul
Description: A Mouse monoclonal antibody against Guinea pig Interleukin 8 (IL8). This antibody is labeled with Biotin.
Interleukin 8 (IL8) Monoclonal Antibody (Rhesus monkey), Biotinylated
4-MAA080Si21-Biotin
Cloud-Clone
EUR 390.00
EUR 3189.60
EUR 932.40
EUR 480.00
EUR 270.00
100ul 10ml 1ml 200ul 20ul
Description: A Mouse monoclonal antibody against Rhesus monkey Interleukin 8 (IL8). This antibody is labeled with Biotin.
Interleukin 8 (IL8) Monoclonal Antibody (Rhesus monkey), Biotinylated
4-MAA080Si22-Biotin
Cloud-Clone
EUR 390.00
EUR 3189.60
EUR 932.40
EUR 480.00
EUR 270.00
100ul 10ml 1ml 200ul 20ul
Description: A Mouse monoclonal antibody against Rhesus monkey Interleukin 8 (IL8). This antibody is labeled with Biotin.
Interleukin 8 (IL8) Monoclonal Antibody (Rhesus monkey), APC-Cy7
4-MAA080Si21-APC-Cy7
Cloud-Clone
EUR 729.60
EUR 8364.00
EUR 2208.00
EUR 976.80
EUR 402.00
100ul 10ml 1ml 200ul 20ul
Description: A Mouse monoclonal antibody against Rhesus monkey Interleukin 8 (IL8). This antibody is labeled with APC-Cy7.
Interleukin 8 (IL8) Monoclonal Antibody (Rhesus monkey), APC-Cy7
4-MAA080Si22-APC-Cy7
Cloud-Clone
EUR 729.60
EUR 8364.00
EUR 2208.00
EUR 976.80
EUR 402.00
100ul 10ml 1ml 200ul 20ul
Description: A Mouse monoclonal antibody against Rhesus monkey Interleukin 8 (IL8). This antibody is labeled with APC-Cy7.
Mouse Anti Human Interleukin-8 Monoclonal Antibody,FITC
CABT-48525MH
Creative Diagnostics
100 TEST
EUR 982.8
Interleukin 10 (IL10) Monoclonal Antibody (Mouse)
4-MAA056Mu21
Cloud-Clone
EUR 296.40
EUR 3012.00
EUR 750.00
EUR 372.00
EUR 256.80
100ul 10ml 1ml 200ul 20ul
Description: A Rat monoclonal antibody against Mouse Interleukin 10 (IL10)
Interleukin 17 (IL17) Monoclonal Antibody (Mouse)
4-MAA063Mu22
Cloud-Clone
EUR 294.00
EUR 2979.60
EUR 742.80
EUR 368.40
EUR 255.60
100ul 10ml 1ml 200ul 20ul
Description: A Rat monoclonal antibody against Mouse Interleukin 17 (IL17)
Interleukin 34 (IL34) Monoclonal Antibody (Mouse)
4-MAC007Mu21
Cloud-Clone
EUR 310.80
EUR 3249.60
EUR 804.00
EUR 393.60
EUR 262.80
100ul 10ml 1ml 200ul 20ul
Description: A Rat monoclonal antibody against Mouse Interleukin 34 (IL34)
Mouse Monoclonal Anti-Human Interleukin-8 IgG
AB-11110
Alpha Diagnostics
100 ug
EUR 416.4
Interleukin 2 (IL2) Monoclonal Antibody (Mouse)
4-MAA073Mu21
Cloud-Clone
EUR 321.60
EUR 3408.00
EUR 840.00
EUR 408.00
EUR 267.60
100ul 10ml 1ml 200ul 20ul
Description: A Rat monoclonal antibody against Mouse Interleukin 2 (IL2)
Interleukin 6 (IL6) Monoclonal Antibody (Mouse)
4-MAA079Mu21
Cloud-Clone
EUR 265.20
EUR 2536.80
EUR 642.00
EUR 328.80
EUR 243.60
100ul 10ml 1ml 200ul 20ul
Description: A Rat monoclonal antibody against Mouse Interleukin 6 (IL6)
Interleukin 10 (IL10) Monoclonal Antibody (Mouse), PE
4-MAA056Mu21-PE
Cloud-Clone
EUR 355.20
EUR 3168.00
EUR 900.00
EUR 446.40
EUR 234.00
100ul 10ml 1ml 200ul 20ul
Description: A Rat monoclonal antibody against Mouse Interleukin 10 (IL10). This antibody is labeled with PE.
Interleukin 17 (IL17) Monoclonal Antibody (Mouse), PE
4-MAA063Mu22-PE
Cloud-Clone
EUR 352.80
EUR 3133.20
EUR 890.40
EUR 442.80
EUR 232.80
100ul 10ml 1ml 200ul 20ul
Description: A Rat monoclonal antibody against Mouse Interleukin 17 (IL17). This antibody is labeled with PE.
Interleukin 34 (IL34) Monoclonal Antibody (Mouse), PE
4-MAC007Mu21-PE
Cloud-Clone
EUR 373.20
EUR 3427.20
EUR 964.80
EUR 471.60
EUR 242.40
100ul 10ml 1ml 200ul 20ul
Description: A Rat monoclonal antibody against Mouse Interleukin 34 (IL34). This antibody is labeled with PE.
Rat Anti Mouse Interleukin-10 Monoclonal Antibody
CABT-48544RM
Creative Diagnostics
0.5 mg
EUR 920.4
Rat Anti Mouse Interleukin-17 Monoclonal Antibody
DMABT-51805RM
Creative Diagnostics
0.5 mg
EUR 1132.8
Mouse Anti Cat Interleukin-2 Monoclonal Antibody
CABT-48481MC
Creative Diagnostics
0.25 mg
EUR 920.4
Interleukin 10 (IL10) Monoclonal Antibody (Mouse), APC
4-MAA056Mu21-APC
Cloud-Clone
EUR 414.00
EUR 3930.00
EUR 1094.40
EUR 528.00
EUR 262.80
100ul 10ml 1ml 200ul 20ul
Description: A Rat monoclonal antibody against Mouse Interleukin 10 (IL10). This antibody is labeled with APC.
Interleukin 10 (IL10) Monoclonal Antibody (Mouse), Cy3
4-MAA056Mu21-Cy3
Cloud-Clone
EUR 502.80
EUR 5190.00
EUR 1410.00
EUR 654.00
EUR 301.20
100ul 10ml 1ml 200ul 20ul
Description: A Rat monoclonal antibody against Mouse Interleukin 10 (IL10). This antibody is labeled with Cy3.
Interleukin 10 (IL10) Monoclonal Antibody (Mouse), HRP
4-MAA056Mu21-HRP
Cloud-Clone
EUR 379.20
EUR 3426.00
EUR 968.40
EUR 477.60
EUR 247.20
100ul 10ml 1ml 200ul 20ul
Description: A Rat monoclonal antibody against Mouse Interleukin 10 (IL10). This antibody is labeled with HRP.
Interleukin 17 (IL17) Monoclonal Antibody (Mouse), APC
4-MAA063Mu22-APC
Cloud-Clone
EUR 410.40
EUR 3886.80
EUR 1083.60
EUR 523.20
EUR 261.60
100ul 10ml 1ml 200ul 20ul
Description: A Rat monoclonal antibody against Mouse Interleukin 17 (IL17). This antibody is labeled with APC.
Interleukin 17 (IL17) Monoclonal Antibody (Mouse), Cy3
4-MAA063Mu22-Cy3
Cloud-Clone
EUR 498.00
EUR 5132.40
EUR 1395.60
EUR 648.00
EUR 298.80
100ul 10ml 1ml 200ul 20ul
Description: A Rat monoclonal antibody against Mouse Interleukin 17 (IL17). This antibody is labeled with Cy3.
Interleukin 17 (IL17) Monoclonal Antibody (Mouse), HRP
4-MAA063Mu22-HRP
Cloud-Clone
EUR 375.60
EUR 3387.60
EUR 958.80
EUR 472.80
EUR 247.20
100ul 10ml 1ml 200ul 20ul
Description: A Rat monoclonal antibody against Mouse Interleukin 17 (IL17). This antibody is labeled with HRP.
Interleukin 34 (IL34) Monoclonal Antibody (Mouse), APC
4-MAC007Mu21-APC
Cloud-Clone
EUR 436.80
EUR 4254.00
EUR 1176.00
EUR 560.40
EUR 272.40
100ul 10ml 1ml 200ul 20ul
Description: A Rat monoclonal antibody against Mouse Interleukin 34 (IL34). This antibody is labeled with APC.
Interleukin 34 (IL34) Monoclonal Antibody (Mouse), Cy3
4-MAC007Mu21-Cy3
Cloud-Clone
EUR 532.80
EUR 5622.00
EUR 1518.00
EUR 697.20
EUR 313.20
100ul 10ml 1ml 200ul 20ul
Description: A Rat monoclonal antibody against Mouse Interleukin 34 (IL34). This antibody is labeled with Cy3.
Interleukin 34 (IL34) Monoclonal Antibody (Mouse), HRP
4-MAC007Mu21-HRP
Cloud-Clone
EUR 398.40
EUR 3706.80
EUR 1039.20
EUR 505.20
EUR 255.60
100ul 10ml 1ml 200ul 20ul
Description: A Rat monoclonal antibody against Mouse Interleukin 34 (IL34). This antibody is labeled with HRP.
Interleukin 2 (IL2) Monoclonal Antibody (Mouse), PE
4-MAA073Mu21-PE
Cloud-Clone
EUR 385.20
EUR 3600.00
EUR 1008.00
EUR 489.60
EUR 247.20
100ul 10ml 1ml 200ul 20ul
Description: A Rat monoclonal antibody against Mouse Interleukin 2 (IL2). This antibody is labeled with PE.
Interleukin 6 (IL6) Monoclonal Antibody (Mouse), PE
4-MAA079Mu21-PE
Cloud-Clone
EUR 319.20
EUR 2649.60
EUR 770.40
EUR 393.60
EUR 218.40
100ul 10ml 1ml 200ul 20ul
Description: A Rat monoclonal antibody against Mouse Interleukin 6 (IL6). This antibody is labeled with PE.
Interleukin 10 (IL10) Monoclonal Antibody (Mouse), FITC
4-MAA056Mu21-FITC
Cloud-Clone
EUR 355.20
EUR 3168.00
EUR 900.00
EUR 446.40
EUR 234.00
100ul 10ml 1ml 200ul 20ul
Description: A Rat monoclonal antibody against Mouse Interleukin 10 (IL10). This antibody is labeled with FITC.
Interleukin 17 (IL17) Monoclonal Antibody (Mouse), FITC
4-MAA063Mu22-FITC
Cloud-Clone
EUR 352.80
EUR 3133.20
EUR 890.40
EUR 442.80
EUR 232.80
100ul 10ml 1ml 200ul 20ul
Description: A Rat monoclonal antibody against Mouse Interleukin 17 (IL17). This antibody is labeled with FITC.
Interleukin 34 (IL34) Monoclonal Antibody (Mouse), FITC
4-MAC007Mu21-FITC
Cloud-Clone
EUR 373.20
EUR 3427.20
EUR 964.80
EUR 471.60
EUR 242.40
100ul 10ml 1ml 200ul 20ul
Description: A Rat monoclonal antibody against Mouse Interleukin 34 (IL34). This antibody is labeled with FITC.
Interleukin 2 (IL2) Monoclonal Antibody (Mouse), APC
4-MAA073Mu21-APC
Cloud-Clone
EUR 452.40
EUR 4470.00
EUR 1230.00
EUR 582.00
EUR 279.60
100ul 10ml 1ml 200ul 20ul
Description: A Rat monoclonal antibody against Mouse Interleukin 2 (IL2). This antibody is labeled with APC.
MET un RON receptoru tirozīna kināzes kolorektālajā adenokarcinomā: molekulāras iespējas kā zāļu mērķi un antivielu un zāļu konjugāti ārstēšanai
Augstākā kolorektālā adenokarcinoma (CRAC), ko raksturo atšķirīgs histopatoloģisks izskats, tālu orgānu metastāzes, iegūta ķīmijrezistence un audzēja ģenētiskais stublājs, ir daudz neviendabīgu vēžu ar atšķirīgiem ģenētiskiem parakstiem un ļaundabīgiem fenotipiem. CRAC terapija onkologiem ir biedējoša darbība.
Šobrīd cīņā pret šo letālo slimību ir izmantotas daudzas metodes kopā ar molekulāro koncentrēšanos uz terapeitisko monoklonālo antivielu, mazmolekulāro kināzes inhibitoru un imūnregulācijas kontrolpunkta līdzekli. Tomēr šīs terapeitiskās metodes un pieejas gūst tikai ierobežotus panākumus. Tādējādi farmaceitiski vēlas atrast jaunus mērķus un izstrādāt jaunus CRAC līdzekļa terapijas līdzekļus. MET un RON receptoru tirozīna kināzes ir iesaistītas CRAC patoģenēzē.
Zinātniskie pētījumi ir atklājuši, ka novirzīta MET un / vai RON ekspresija un signalizācija ir būtiska, regulējot CRAC attīstību un ļaundabīgos fenotipus. Paaugstinātai MET un / vai RON izteiksmei ir arī CRAC attīstības un skartās personas izdzīvošanas prognozes vērtība.
Šīs iespējas piedāvā loģisko pamatu koncentrēties uz TER un RON zinātniskai CRAC iejaukšanai. Pašlaik, izmantojot mazmolekulārās kināzes inhibitorus, koncentrējoties uz MET CRAC terapijai, ir panākts būtisks progress, saņemot vairākus apstiprinājumus zinātniskai lietošanai.
Neskatoties uz to, uz antivielām balstītie bioterapeitiskie līdzekļi, lai arī zinātniski pētījumi veikti vairāk nekā astoņus gadus, ir guvuši nelielu progresu vai nav devuši nekādu progresu. Šajā novērtējumā mēs koncentrējamies uz MET un / vai RON nozīmi CRAC audzēja veidošanā un anti-MET, anti-RON un MET un RON-dual augšanu, koncentrējoties uz antivielu un zāļu konjugātiem zinātniskai lietderībai. Katra preklīniskā un zinātniskā pētījuma secinājumi agrāk vai vēlāk atklāj šī jaunā veida bioterapeitisko līdzekļu potenciālu CRAC ārstēšanai.
Seruma anti-Neu5Gc antivielu afinitātes attīrīšana atklāja paaugstinātu diapazonu un neobjektīvus masīvu repertuāra modeļus cilvēkiem , kuriem palielinājās Neu5Gc diapazons, bez antivielu afinitātes palielināšanās. Turklāt augsta gaļas svara samazināšanas plānā antivielu daudzveidības modeļi uz glikāna mikroelementiem mainījās ar Neu5Gcα3 saistīto glikānu virzienā, paaugstinot α3 / α6-glikānu attiecību.
Secinājumi : Mēs atklājām pārredzamu hipersaiti starp grādiem un seruma anti-Neu5Gc IgG un Neu5Gc patēriņu no rozā gaļas un piena produktiem. Šīs precīzās racionālās metodikas ļāva izstrādāt Gcemicindeksu, lai vienkāršotu Neu5Gc novērtēšanu ēdienreizēs, kas, bez šaubām, būtu pielāgots uztura ieteikumiem, lai samazinātu lielāko daļu vēža risku.
Antivielu reakcija uz suņu parvovīrusa vakcināciju suņiem ar hiperadrenokortikismu, kas tiek ārstēta ar Trilostane
Nav zināms, kā suņi ar hiperadrenokortikismu (HAC) reaģē uz vakcināciju. Šajā pētījumā tika izmērītas antivielas pretstatā suņu parvovīrusam (CPV) suņiem ar HAC, kas ar trilostānu apstrādāts agrāk un pēc CPV vakcinācijas, un atšķirībā no imūnās atbildes reakcijas uz veselīgu suņu reakciju.
Vienpadsmit ilkņi ar HAC un pilnvērtīgi vecumam atbilstoši suņi (n = 31) ieguva modificētu dzīvo CPV vakcīnu. Antivielas ir izlemtas 0., 7. un 28. dienā ar hemaglutinācijas inhibīciju. Lai saskaņotu suņu imūnreakciju ar HAC un pilnvērtīgiem ilkņiem, tika izmantots vienveidīgais novērtējums.Pirmsvakcinācijas antivielas (≥10) ir atklātas 100% suņu ar HAC (11/11; 95% TI: 70,0-100) un 93,5% pilnvērtīgu suņu (29/31; 95% TI: 78,3- 99.2). Suņiem ar HAC netika novērota ≥Four reizes lielāka antivielu titra palielināšanās, turpretī 22,6% pilnvērtīgu ilkņu gadījumā ≥Four reizes titra palielināšanās tika novērota (7/31; 95% TI: 11,1-40,1).
Maigi ar vakcīnu saistīti antagonistiski gadījumi (VAAE) ir konstatēti 54,5% suņu ar HAC (6/11; 95% TI: 28,0-78,8) un 29,0% pilnvērtīgu ilkņu (9/31; 95% TI: 15,9) -46,8). Nebija būtiskas atšķirības pirmsvakcinācijas antivielu klātbūtnē (p = 1.000), atbildes reakcija uz vakcināciju (p = 0.161), kā arī VAAE izplatības ziņā (p = 0.158). Imūnsistēmas suņu darbība ar HAC, kas apstrādāta ar trilostānu, šķiet līdzīga veselīgu ilkņu darbībai.
Linkeru izstrāde un validācija vietņu specifiskai antivielu-narkotiku konjugātu sagatavošanai, kas satur vairākas zāļu kopijas vienā cisteīna konjugācijas vietnē
Pirmās paaudzes cisteīna bāzes specifisko antivielu un zāļu konjugāti (ADC) ir ierobežoti līdz 1 narkotikai uz vienu cisteīnu. Neskatoties uz to, noteiktiem mērķiem nepieciešama pārmērīga zāļu un antivielu attiecība (DAR), kas atbilst zemas jaudas kravām. Palielinātu zāļu slodzi var panākt, izmantojot klasiskās cisteīna konjugācijas stratēģijas, tomēr tās noved pie neviendabīguma, neoptimālas efektivitātes un farmakokinētikas.
Šeit mēs aprakstām to heterobifunkcionālo saišu dizainu, sintēzi un apstiprināšanu, kuras var izmantot ADC ar divu, trīs un Four DAR sagatavošanai, katrai vietnei raksturīgā metodē vienā cisteīna konjugācijas vietnē, kas noved pie vietnei specifiskiem ADC ar DAR 4, seši un astoņi. Izstrādātie saites satur sulfhidrilam raksturīgu jodoacetilreaktīvu grupu un vairākas cikliskas diēna daļas, kas, izmantojot Dīla-Aldera reakciju, varētu efektīvi reaģēt ar lietderīgo slodzi ar maleimīdu nesošajām kravām.
Kā idejas pierādījumu mēs sintezējām vietnei specifiskus DAR 4, sešus un astoņus ADC, kas satur tubulizīnu (AZ13601508), izmantojot inženierijas antivielas ar cisteīnu, kas ievietots aiz 239. vietas antivielu CH2 zonā.
Mēs novērtējām un atšķirībā no tā ADC in vitro citotoksicitāti, kas iegūta, izmantojot šeit aprakstīto vietnei specifisko platformu, ar ADC, kas gatavi izmantot klasisko cisteīna konjugāciju. Mūsu zināšanas apstiprināja jaunu konjugācijas platformu, kuras pamatā ir cisteīns, vietnei specifisku ADC sagatavošanai ar pārmērīgu zāļu slodzi terapeitiskos nolūkos.
Protectin (CD59) Monoclonal Antibody (Rabbit), APC
4-MAB336Rb21-APC
Cloud-Clone
EUR 422.40
EUR 4059.60
EUR 1126.80
EUR 540.00
EUR 267.60
100ul 10ml 1ml 200ul 20ul
Description: A Mouse monoclonal antibody against Rabbit Protectin (CD59). This antibody is labeled with APC.
Protectin (CD59) Monoclonal Antibody (Rabbit), Cy3
4-MAB336Rb21-Cy3
Cloud-Clone
EUR 513.60
EUR 5362.80
EUR 1453.20
EUR 670.80
EUR 306.00
100ul 10ml 1ml 200ul 20ul
Description: A Mouse monoclonal antibody against Rabbit Protectin (CD59). This antibody is labeled with Cy3.
Protectin (CD59) Monoclonal Antibody (Rabbit), HRP
4-MAB336Rb21-HRP
Cloud-Clone
EUR 386.40
EUR 3537.60
EUR 996.00
EUR 488.40
EUR 252.00
100ul 10ml 1ml 200ul 20ul
Description: A Mouse monoclonal antibody against Rabbit Protectin (CD59). This antibody is labeled with HRP.
Protectin (CD59) Monoclonal Antibody (Rabbit), FITC
4-MAB336Rb21-FITC
Cloud-Clone
EUR 362.40
EUR 3271.20
EUR 925.20
EUR 456.00
EUR 237.60
100ul 10ml 1ml 200ul 20ul
Description: A Mouse monoclonal antibody against Rabbit Protectin (CD59). This antibody is labeled with FITC.
Protectin (CD59) Monoclonal Antibody (Rabbit), Biotinylated
4-MAB336Rb21-Biotin
Cloud-Clone
EUR 379.20
EUR 3046.80
EUR 896.40
EUR 465.60
EUR 265.20
100ul 10ml 1ml 200ul 20ul
Description: A Mouse monoclonal antibody against Rabbit Protectin (CD59). This antibody is labeled with Biotin.
Protectin (CD59) Monoclonal Antibody (Rabbit), APC-Cy7
4-MAB336Rb21-APC-Cy7
Cloud-Clone
EUR 702.00
EUR 7975.20
EUR 2110.80
EUR 937.20
EUR 391.20
100ul 10ml 1ml 200ul 20ul
Description: A Mouse monoclonal antibody against Rabbit Protectin (CD59). This antibody is labeled with APC-Cy7.
Anti-CD59 / Complement Regulatory Protein / Protectin Monoclonal Antibody
M00914
BosterBio
100ug/vial
EUR 476.4
Description: Mouse Monoclonal CD59 / Complement Regulatory Protein / Protectin Antibody. Validated in IF, IHC and tested in Human.
Monoclonal CD59 / Complement Regulatory Protein / Protectin Antibody, Clone: MACIF/629
AMM01596G
Leading Biology
7 ml
EUR 580.8
Description: A Monoclonal antibody against Human CD59 / Complement Regulatory Protein / Protectin. The antibodies are raised in Mouse and are from clone MACIF/629. This antibody is applicable in IHC, IF, FC
Monoclonal CD59 / Complement Regulatory Protein / Protectin Antibody, Clone: MACIF/1193
AMM01601G
Leading Biology
7 ml
EUR 580.8
Description: A Monoclonal antibody against Human CD59 / Complement Regulatory Protein / Protectin. The antibodies are raised in Mouse and are from clone MACIF/1193. This antibody is applicable in IHC, IF, FC
Monoclonal CD59 / Complement Regulatory Protein / Protectin Antibody - With BSA and Azide, Clone: SPM616
AMM01599G
Leading Biology
0.05mg
EUR 475.2
Description: A Monoclonal antibody against Human CD59 / Complement Regulatory Protein / Protectin - With BSA and Azide. The antibodies are raised in Mouse and are from clone SPM616. This antibody is applicable in IHC, IF, FC
Monoclonal CD59 / Complement Regulatory Protein / Protectin Antibody - With BSA and Azide, Clone: 193-27
AMM01592G
Leading Biology
0.05mg
EUR 475.2
Description: A Monoclonal antibody against Human CD59 / Complement Regulatory Protein / Protectin - With BSA and Azide. The antibodies are raised in Mouse and are from clone 193-27. This antibody is applicable in IF, FC
Monoclonal CD59 / Complement Regulatory Protein / Protectin Antibody - Without BSA and Azide, Clone: SPM616
AMM01600G
Leading Biology
0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human CD59 / Complement Regulatory Protein / Protectin - Without BSA and Azide. The antibodies are raised in Mouse and are from clone SPM616. This antibody is applicable in IHC, IF, FC
Monoclonal CD59 / Complement Regulatory Protein / Protectin Antibody - Without BSA and Azide, Clone: 193-27
AMM01593G
Leading Biology
0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human CD59 / Complement Regulatory Protein / Protectin - Without BSA and Azide. The antibodies are raised in Mouse and are from clone 193-27. This antibody is applicable in IF, FC
Monoclonal CD59 / Complement Regulatory Protein / Protectin Antibody - With BSA and Azide, Clone: BRA-10G
AMM01594G
Leading Biology
0.05mg
EUR 475.2
Description: A Monoclonal antibody against Human CD59 / Complement Regulatory Protein / Protectin - With BSA and Azide. The antibodies are raised in Mouse and are from clone BRA-10G. This antibody is applicable in IF, FC
Monoclonal CD59 / Complement Regulatory Protein / Protectin Antibody - With BSA and Azide, Clone: MACIF/629
AMM01597G
Leading Biology
0.05mg
EUR 475.2
Description: A Monoclonal antibody against Human CD59 / Complement Regulatory Protein / Protectin - With BSA and Azide. The antibodies are raised in Mouse and are from clone MACIF/629. This antibody is applicable in IHC, IF, FC
Monoclonal CD59 / Complement Regulatory Protein / Protectin Antibody - With BSA and Azide, Clone: MACIF/1193
AMM01602G
Leading Biology
0.05mg
EUR 475.2
Description: A Monoclonal antibody against Human CD59 / Complement Regulatory Protein / Protectin - With BSA and Azide. The antibodies are raised in Mouse and are from clone MACIF/1193. This antibody is applicable in IHC, IF, FC
Monoclonal CD59 / Complement Regulatory Protein / Protectin Antibody - Without BSA and Azide, Clone: BRA-10G
AMM01595G
Leading Biology
0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human CD59 / Complement Regulatory Protein / Protectin - Without BSA and Azide. The antibodies are raised in Mouse and are from clone BRA-10G. This antibody is applicable in IF, FC
Monoclonal CD59 / Complement Regulatory Protein / Protectin Antibody - Without BSA and Azide, Clone: MACIF/629
AMM01598G
Leading Biology
0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human CD59 / Complement Regulatory Protein / Protectin - Without BSA and Azide. The antibodies are raised in Mouse and are from clone MACIF/629. This antibody is applicable in IHC, IF, FC
Monoclonal CD59 / Complement Regulatory Protein / Protectin Antibody - Without BSA and Azide, Clone: MACIF/1193
AMM01603G
Leading Biology
0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human CD59 / Complement Regulatory Protein / Protectin - Without BSA and Azide. The antibodies are raised in Mouse and are from clone MACIF/1193. This antibody is applicable in IHC, IF, FC
Protectin (CD59) Polyclonal Antibody (Mouse)
4-PAB336Mu01
Cloud-Clone
EUR 291.60
EUR 2948.40
EUR 735.60
EUR 366.00
EUR 254.40
100ul 10ml 1ml 200ul 20ul
Description: A Rabbit polyclonal antibody against Mouse Protectin (CD59)
Protectin (CD59) Antibody
abx200391-100ug
Abbexa
100 ug
EUR 393.6
Protectin (CD59) Antibody
20-abx210170
Abbexa
Protectin (CD59) Antibody
20-abx210424
Abbexa
Protectin (CD59) Antibody
20-abx270064
Abbexa
EUR 560.40
EUR 644.40
EUR 326.40
EUR 978.00
EUR 427.20
100 tests 200 tests 25 tests 500 tests 50 tests
Protectin (CD59) Antibody
abx231489-100ug
Abbexa
100 ug
EUR 577.2
Protectin (CD59) Antibody
20-abx225094
Abbexa
EUR 444.00
EUR 727.20
EUR 376.80
Protectin (CD59) Antibody
20-abx109633
Abbexa
EUR 493.20
EUR 2214.00
EUR 718.80
EUR 218.40
EUR 360.00
100 ug 1 mg 200 ug 20 ug 50 ug
Protectin (CD59) Antibody
20-abx109634
Abbexa
EUR 493.20
EUR 2214.00
EUR 718.80
EUR 218.40
EUR 360.00
100 ug 1 mg 200 ug 20 ug 50 ug
Protectin (CD59) Antibody
20-abx100397
Abbexa
EUR 493.20
EUR 159.60
EUR 1378.80
EUR 678.00
EUR 376.80
100 ug 10 ug 1 mg 200 ug 50 ug
Protectin (CD59) Antibody
20-abx100398
Abbexa
