HER2 ātras internalizācijas un novirzītas cilvēku tirdzniecības molekulārais

HER2 ātras internalizācijas un novirzītas cilvēku tirdzniecības molekulārais mehānisms, ko izraisa anti-HER2 biparatopiskais antiviela

  • HER2 (cilvēka epidermas attīstības problēmas 2. receptora), ErbB2 receptoru tirozīna kināzes, pastiprināšanās un pārmērīga ekspresija ir saistīta ar lielāko daļu cilvēku vēža un metastāžu. Ir ziņots, ka bispecifiska četrvērtīga anti-HER2 antiviela (anti-HER2-Bs), kas koncentrējas uz diviem HER2 nepilējošiem epitopiem IV zonā (trastuzumabs) un II zonā (39S), izraisa ātru HER2 internalizāciju un videi draudzīgu degradāciju. receptori. 
  • Šajā pētījumā mēs izpētījām šīs antivielu izraisītās ātrās HER2 internalizācijas un intracelulārās tirdzniecības molekulāro mehānismu. Izmantojot kvantitatīvo fluorescējošo attēlveidošanu, mēs pretstatām anti-HER2-B un tā vecāku roku antivielu internalizācijas kinētikai atsevišķi vai maisījumos un daudzos internalizāciju veicinošos apstākļos. Rezultāti parādīja, ka ātrai anti-HER2-B internalizācijai izšķiroša nozīme bija vienlaicīgai katra epitopa iesaistei.
  • Anti-HER2-B un vecāku roku antivielu mobilā uzņemšana notika no klatrīna atkarīgas endocitozes veidā; tomēr antivielas šūnās satur pilnīgi atšķirīgus cilvēku tirdzniecības ceļus. Trastuzumabs 2 stundu laikā disociējās no HER2, ļaujot receptoriem atkārtoti pārstrādāt, savukārt anti-HER2-B palika saistīti ar receptoru visā endocītiskajā ceļā, pārdodot receptoru ubikvitināciju, tirdzniecību ar lizosomām un videi draudzīgu noārdīšanos.
  • Atbilstoši HER2 novirzīšanai uz degradāciju, anti-HER2-B ievērojami samazināja HER2 izdalīšanos un mainīja tā eksosomālo eksportu. Kopā šie rezultāti ļauj labāk izprast anti-Her2-B kustības mehānismu un var sniegt informāciju par racionālu anti-HER2 terapijas dizainu papildus dažādām bispecifiskām molekulām.

Cilvēkiem ar receptoru saistošās domēna specifiskās neitralizējošās monoklonālās antivielas pretstatā SARS-CoV un SARS-CoV-2

Ārkārtējā akūtā elpošanas sindroma (SARS) un 2019. gada koronavīrusa slimības (COVID-19) uzliesmojumi, ko izraisīja attiecīgi SARS-CoV un SARS-CoV-2, ir ārkārtīgi apdraudējuši pasaules sabiedrības labklājību un ekonomisko sistēmu. Šo vīrusu slimību terapija un profilakse ir cilvēka neitralizējošo monoklonālo antivielu (NMAbs) analīze un augšana.

Zinātnieki ir skrīnējuši neitralizējošās antivielas, kā antigēnu izmantojot vīrusa receptoru saistošo zonu (RBD), norādot, ka RBD ir iekļauti vairāki konformācijas neitralizējoši epitopi, kas ir galvenie strukturālie domēni neitralizējošo antivielu un T-šūnu imūnreakciju inducēšanai. Šajā novērtējumā ir apkopota RBD un RBD specifisko NMAb konstrukcija un veiktspēja, pretstatā SARS-CoV un SARS-CoV-2 pašlaik zem izaugsmes.

bernsklepo
bernsklepo

Equine Interleukin 8 (IL8) ELISA Kit

RD-IL8-Eq-48Tests 48 Tests
EUR 505

Equine Interleukin 8 (IL8) ELISA Kit

RD-IL8-Eq-96Tests 96 Tests
EUR 700

Human Interleukin 8 (IL8) ELISA Kit

RD-IL8-Hu-48Tests 48 Tests
EUR 313

Human Interleukin 8 (IL8) ELISA Kit

RD-IL8-Hu-96Tests 96 Tests
EUR 426

Porcine Interleukin 8 (IL8) ELISA Kit

RD-IL8-p-48Tests 48 Tests
EUR 443

Porcine Interleukin 8 (IL8) ELISA Kit

RD-IL8-p-96Tests 96 Tests
EUR 612

Rabbit Interleukin 8 (IL8) ELISA Kit

RD-IL8-Rb-48Tests 48 Tests
EUR 450

Rabbit Interleukin 8 (IL8) ELISA Kit

RD-IL8-Rb-96Tests 96 Tests
EUR 622

Monkey Interleukin 8 (IL8) ELISA Kit

RD-IL8-Si-48Tests 48 Tests
EUR 472

Monkey Interleukin 8 (IL8) ELISA Kit

RD-IL8-Si-96Tests 96 Tests
EUR 653

Bovine Interleukin 8 (IL8) ELISA Kit

DLR-IL8-b-48T 48T
EUR 403
Description: A sandwich quantitative ELISA assay kit for detection of Bovine Interleukin 8 (IL8) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Bovine Interleukin 8 (IL8) ELISA Kit

DLR-IL8-b-96T 96T
EUR 517
Description: A sandwich quantitative ELISA assay kit for detection of Bovine Interleukin 8 (IL8) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Canine Interleukin 8 (IL8) ELISA Kit

DLR-IL8-c-48T 48T
EUR 326
Description: A sandwich quantitative ELISA assay kit for detection of Canine Interleukin 8 (IL8) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Canine Interleukin 8 (IL8) ELISA Kit

DLR-IL8-c-96T 96T
EUR 411
Description: A sandwich quantitative ELISA assay kit for detection of Canine Interleukin 8 (IL8) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Chicken Interleukin 8 (IL8) ELISA Kit

DLR-IL8-Ch-48T 48T
EUR 413
Description: A sandwich quantitative ELISA assay kit for detection of Chicken Interleukin 8 (IL8) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Chicken Interleukin 8 (IL8) ELISA Kit

DLR-IL8-Ch-96T 96T
EUR 531
Description: A sandwich quantitative ELISA assay kit for detection of Chicken Interleukin 8 (IL8) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Equine Interleukin 8 (IL8) ELISA Kit

DLR-IL8-Eq-48T 48T
EUR 503
Description: A sandwich quantitative ELISA assay kit for detection of Equine Interleukin 8 (IL8) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Equine Interleukin 8 (IL8) ELISA Kit

DLR-IL8-Eq-96T 96T
EUR 654
Description: A sandwich quantitative ELISA assay kit for detection of Equine Interleukin 8 (IL8) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Fish Interleukin 8 (IL8) ELISA Kit

DLR-IL8-Fi-48T 48T
EUR 503
Description: A sandwich quantitative ELISA assay kit for detection of Fish Interleukin 8 (IL8) in samples from serum, plasma, tissue homogenates or other biological fluids.

Fish Interleukin 8 (IL8) ELISA Kit

DLR-IL8-Fi-96T 96T
EUR 654
Description: A sandwich quantitative ELISA assay kit for detection of Fish Interleukin 8 (IL8) in samples from serum, plasma, tissue homogenates or other biological fluids.

Human Interleukin 8 (IL8) ELISA Kit

DLR-IL8-Hu-48T 48T
EUR 333
Description: A sandwich quantitative ELISA assay kit for detection of Human Interleukin 8 (IL8) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Human Interleukin 8 (IL8) ELISA Kit

DLR-IL8-Hu-96T 96T
EUR 420
Description: A sandwich quantitative ELISA assay kit for detection of Human Interleukin 8 (IL8) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Porcine Interleukin 8 (IL8) ELISA Kit

DLR-IL8-p-48T 48T
EUR 448
Description: A sandwich quantitative ELISA assay kit for detection of Porcine Interleukin 8 (IL8) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Porcine Interleukin 8 (IL8) ELISA Kit

DLR-IL8-p-96T 96T
EUR 579
Description: A sandwich quantitative ELISA assay kit for detection of Porcine Interleukin 8 (IL8) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Rabbit Interleukin 8 (IL8) ELISA Kit

DLR-IL8-Rb-48T 48T
EUR 454
Description: A sandwich quantitative ELISA assay kit for detection of Rabbit Interleukin 8 (IL8) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Rabbit Interleukin 8 (IL8) ELISA Kit

DLR-IL8-Rb-96T 96T
EUR 587
Description: A sandwich quantitative ELISA assay kit for detection of Rabbit Interleukin 8 (IL8) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Monkey Interleukin 8 (IL8) ELISA Kit

DLR-IL8-Si-48T 48T
EUR 474
Description: A sandwich quantitative ELISA assay kit for detection of Monkey Interleukin 8 (IL8) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Monkey Interleukin 8 (IL8) ELISA Kit

DLR-IL8-Si-96T 96T
EUR 614
Description: A sandwich quantitative ELISA assay kit for detection of Monkey Interleukin 8 (IL8) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Bovine Interleukin 8 (IL8) ELISA Kit

RDR-IL8-b-48Tests 48 Tests
EUR 409

Bovine Interleukin 8 (IL8) ELISA Kit

RDR-IL8-b-96Tests 96 Tests
EUR 563

Canine Interleukin 8 (IL8) ELISA Kit

RDR-IL8-c-48Tests 48 Tests
EUR 318

Canine Interleukin 8 (IL8) ELISA Kit

RDR-IL8-c-96Tests 96 Tests
EUR 433

Chicken Interleukin 8 (IL8) ELISA Kit

RDR-IL8-Ch-48Tests 48 Tests
EUR 422

Chicken Interleukin 8 (IL8) ELISA Kit

RDR-IL8-Ch-96Tests 96 Tests
EUR 581

Equine Interleukin 8 (IL8) ELISA Kit

RDR-IL8-Eq-48Tests 48 Tests
EUR 528

Equine Interleukin 8 (IL8) ELISA Kit

RDR-IL8-Eq-96Tests 96 Tests
EUR 733

Fish Interleukin 8 (IL8) ELISA Kit

RDR-IL8-Fi-48Tests 48 Tests
EUR 528

Fish Interleukin 8 (IL8) ELISA Kit

RDR-IL8-Fi-96Tests 96 Tests
EUR 733

Human Interleukin 8 (IL8) ELISA Kit

RDR-IL8-Hu-48Tests 48 Tests
EUR 326

Human Interleukin 8 (IL8) ELISA Kit

RDR-IL8-Hu-96Tests 96 Tests
EUR 445

Porcine Interleukin 8 (IL8) ELISA Kit

RDR-IL8-p-48Tests 48 Tests
EUR 463

Porcine Interleukin 8 (IL8) ELISA Kit

RDR-IL8-p-96Tests 96 Tests
EUR 640

Rabbit Interleukin 8 (IL8) ELISA Kit

RDR-IL8-Rb-48Tests 48 Tests
EUR 470

Rabbit Interleukin 8 (IL8) ELISA Kit

RDR-IL8-Rb-96Tests 96 Tests
EUR 651

Monkey Interleukin 8 (IL8) ELISA Kit

RDR-IL8-Si-48Tests 48 Tests
EUR 493

Monkey Interleukin 8 (IL8) ELISA Kit

RDR-IL8-Si-96Tests 96 Tests
EUR 683

Interleukin 8 (IL8) Monoclonal Antibody (Horse)

4-MAA080Eq21
  • EUR 271.00
  • EUR 2892.00
  • EUR 712.00
  • EUR 344.00
  • EUR 224.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Horse Interleukin 8 (IL8)

Interleukin 8 (IL8) Monoclonal Antibody (Chicken)

4-MAA080Ga22
  • EUR 236.00
  • EUR 2338.00
  • EUR 586.00
  • EUR 294.00
  • EUR 209.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Chicken Interleukin 8 (IL8)

Interleukin 8 (IL8) Monoclonal Antibody (Human)

4-MAA080Hu22
  • EUR 221.00
  • EUR 2114.00
  • EUR 535.00
  • EUR 274.00
  • EUR 203.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Human Interleukin 8 (IL8)

Interleukin 8 (IL8) Monoclonal Antibody (Human)

4-MAA080Hu24
  • EUR 221.00
  • EUR 2114.00
  • EUR 535.00
  • EUR 274.00
  • EUR 203.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Human Interleukin 8 (IL8)

Interleukin 8 (IL8) Monoclonal Antibody (Pig)

4-MAA080Po22
  • EUR 249.00
  • EUR 2549.00
  • EUR 634.00
  • EUR 313.00
  • EUR 215.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Pig Interleukin 8 (IL8)

Interleukin 8 (IL8) Monoclonal Antibody (Pig)

4-MAA080Po24
  • EUR 249.00
  • EUR 2549.00
  • EUR 634.00
  • EUR 313.00
  • EUR 215.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Pig Interleukin 8 (IL8)

Interleukin 8 (IL8) Monoclonal Antibody (Pig)

4-MAA080Po26
  • EUR 249.00
  • EUR 2549.00
  • EUR 634.00
  • EUR 313.00
  • EUR 215.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Pig Interleukin 8 (IL8)

Interleukin 8 (IL8) Monoclonal Antibody (Rabbit)

4-MAA080Rb22
  • EUR 251.00
  • EUR 2589.00
  • EUR 643.00
  • EUR 317.00
  • EUR 216.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Rabbit Interleukin 8 (IL8)

Guinea pig Interleukin 8 (IL8) ELISA Kit

RD-IL8-Gu-48Tests 48 Tests
EUR 375

Guinea pig Interleukin 8 (IL8) ELISA Kit

RD-IL8-Gu-96Tests 96 Tests
EUR 515

Guinea pig Interleukin 8 (IL8) ELISA Kit

DLR-IL8-Gu-48T 48T
EUR 388
Description: A sandwich quantitative ELISA assay kit for detection of Guinea pig Interleukin 8 (IL8) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Guinea pig Interleukin 8 (IL8) ELISA Kit

DLR-IL8-Gu-96T 96T
EUR 496
Description: A sandwich quantitative ELISA assay kit for detection of Guinea pig Interleukin 8 (IL8) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Guinea pig Interleukin 8 (IL8) ELISA Kit

RDR-IL8-Gu-48Tests 48 Tests
EUR 391

Guinea pig Interleukin 8 (IL8) ELISA Kit

RDR-IL8-Gu-96Tests 96 Tests
EUR 538

Interleukin 8 (IL8) Antibody

20-abx100960
  • EUR 314.00
  • EUR 133.00
  • EUR 829.00
  • EUR 425.00
  • EUR 272.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Interleukin 8 (IL8) Antibody

20-abx100961
  • EUR 411.00
  • EUR 133.00
  • EUR 1121.00
  • EUR 551.00
  • EUR 314.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Interleukin 8 (IL8) Antibody

20-abx100962
  • EUR 411.00
  • EUR 133.00
  • EUR 1121.00
  • EUR 551.00
  • EUR 314.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Interleukin 8 (IL8) Antibody

20-abx100963
  • EUR 300.00
  • EUR 704.00
  • EUR 356.00
  • EUR 154.00
  • EUR 244.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Interleukin 8 (IL8) Antibody

20-abx100964
  • EUR 300.00
  • EUR 704.00
  • EUR 356.00
  • EUR 154.00
  • EUR 244.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Interleukin 8 (IL8) Antibody

20-abx100965
  • EUR 398.00
  • EUR 133.00
  • EUR 1066.00
  • EUR 523.00
  • EUR 300.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Interleukin 8 (IL8) Antibody

20-abx100966
  • EUR 314.00
  • EUR 773.00
  • EUR 411.00
  • EUR 154.00
  • EUR 258.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Interleukin 8 (IL8) Antibody

20-abx100967
  • EUR 411.00
  • EUR 133.00
  • EUR 1163.00
  • EUR 565.00
  • EUR 314.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Interleukin 8 (IL8) Antibody

20-abx100969
  • EUR 439.00
  • EUR 133.00
  • EUR 1233.00
  • EUR 592.00
  • EUR 328.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Interleukin 8 (IL8) Antibody

20-abx100970
  • EUR 342.00
  • EUR 871.00
  • EUR 453.00
  • EUR 154.00
  • EUR 272.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Interleukin 8 (IL8) Antibody

20-abx100971
  • EUR 453.00
  • EUR 133.00
  • EUR 1316.00
  • EUR 634.00
  • EUR 342.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Interleukin 8 (IL8) Antibody

20-abx100972
  • EUR 467.00
  • EUR 133.00
  • EUR 1372.00
  • EUR 648.00
  • EUR 356.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Interleukin 8 (IL8) Antibody

abx036426-100ug 100 ug
EUR 391

Interleukin 8 (IL8) Antibody

20-abx131832
  • EUR 356.00
  • EUR 926.00
  • EUR 467.00
  • EUR 154.00
  • EUR 272.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Interleukin 8 (IL8) Antibody

20-abx131833
  • EUR 342.00
  • EUR 871.00
  • EUR 453.00
  • EUR 154.00
  • EUR 272.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Interleukin 8 (IL8) Antibody

20-abx131834
  • EUR 328.00
  • EUR 829.00
  • EUR 425.00
  • EUR 154.00
  • EUR 258.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Interleukin 8 (IL8) Antibody

20-abx131835
  • EUR 328.00
  • EUR 843.00
  • EUR 439.00
  • EUR 154.00
  • EUR 258.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Interleukin 8 (IL8) Antibody

20-abx131836
  • EUR 342.00
  • EUR 871.00
  • EUR 453.00
  • EUR 154.00
  • EUR 272.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Interleukin 8 (IL8) Antibody

20-abx131837
  • EUR 342.00
  • EUR 871.00
  • EUR 453.00
  • EUR 154.00
  • EUR 272.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Interleukin 8 (IL8) Antibody

20-abx131838
  • EUR 300.00
  • EUR 704.00
  • EUR 356.00
  • EUR 154.00
  • EUR 244.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Interleukin 8 (IL8) Antibody

20-abx131839
  • EUR 328.00
  • EUR 829.00
  • EUR 425.00
  • EUR 154.00
  • EUR 258.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Interleukin 8 (IL8) Antibody

20-abx131840
  • EUR 328.00
  • EUR 829.00
  • EUR 425.00
  • EUR 154.00
  • EUR 258.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Interleukin 8 (IL8) Antibody

20-abx137023
  • EUR 356.00
  • EUR 523.00
  • 0.5 mg
  • 1 mg

Interleukin 8 (IL8) Antibody

20-abx009111
  • EUR 300.00
  • EUR 439.00
  • EUR 189.00
  • 100 ul
  • 200 ul
  • 30 ul

Interleukin 8 (IL8) Antibody

abx018002-100ug 100 ug
EUR 342

Interleukin 8 (IL8) Antibody

abx020956-05mg 0.5 mg
EUR 1080

Interleukin 8 (IL8) Antibody

20-abx270103
  • EUR 467.00
  • EUR 537.00
  • EUR 272.00
  • EUR 815.00
  • EUR 356.00
  • 100 tests
  • 200 tests
  • 25 tests
  • 500 tests
  • 50 tests

Interleukin 8 (IL8) Antibody

20-abx270152
  • EUR 467.00
  • EUR 537.00
  • EUR 272.00
  • EUR 815.00
  • EUR 356.00
  • 100 tests
  • 200 tests
  • 25 tests
  • 500 tests
  • 50 tests

Interleukin 8 (IL8) Antibody

20-abx270200
  • EUR 467.00
  • EUR 537.00
  • EUR 272.00
  • EUR 815.00
  • EUR 356.00
  • 100 tests
  • 200 tests
  • 25 tests
  • 500 tests
  • 50 tests

Interleukin 8 (IL8) Antibody

20-abx270201
  • EUR 467.00
  • EUR 537.00
  • EUR 272.00
  • EUR 815.00
  • EUR 356.00
  • 100 tests
  • 200 tests
  • 25 tests
  • 500 tests
  • 50 tests

Interleukin 8 (IL8) Antibody

20-abx177199
  • EUR 356.00
  • EUR 133.00
  • EUR 1038.00
  • EUR 523.00
  • EUR 300.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Interleukin 8 (IL8) Antibody

20-abx177201
  • EUR 1191.00
  • EUR 578.00
  • 1 mg
  • 200 ug

Interleukin 8 (IL8) Antibody

20-abx173191
  • EUR 356.00
  • EUR 913.00
  • EUR 467.00
  • EUR 154.00
  • EUR 272.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Interleukin 8 (IL8) Antibody

abx216289-100ug 100 ug
EUR 439

Interleukin 8 (IL8) Monoclonal Antibody (Human, Dog)

4-MAA080Ca22
  • EUR 221.00
  • EUR 2114.00
  • EUR 535.00
  • EUR 274.00
  • EUR 203.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Human, Dog Interleukin 8 (IL8)

Interleukin 8 (IL8) Monoclonal Antibody (Horse), APC

4-MAA080Eq21-APC
  • EUR 382.00
  • EUR 3797.00
  • EUR 1043.00
  • EUR 492.00
  • EUR 234.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Horse Interleukin 8 (IL8). This antibody is labeled with APC.

Interleukin 8 (IL8) Monoclonal Antibody (Horse), Biotinylated

4-MAA080Eq21-Biotin
  • EUR 338.00
  • EUR 2842.00
  • EUR 823.00
  • EUR 419.00
  • EUR 230.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Horse Interleukin 8 (IL8). This antibody is labeled with Biotin.

Interleukin 8 (IL8) Monoclonal Antibody (Horse), Cy3

4-MAA080Eq21-Cy3
  • EUR 468.00
  • EUR 5021.00
  • EUR 1349.00
  • EUR 614.00
  • EUR 271.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Horse Interleukin 8 (IL8). This antibody is labeled with Cy3.

Interleukin 8 (IL8) Monoclonal Antibody (Horse), FITC

4-MAA080Eq21-FITC
  • EUR 325.00
  • EUR 3057.00
  • EUR 854.00
  • EUR 413.00
  • EUR 207.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Horse Interleukin 8 (IL8). This antibody is labeled with FITC.

Interleukin 8 (IL8) Monoclonal Antibody (Horse), HRP

4-MAA080Eq21-HRP
  • EUR 348.00
  • EUR 3307.00
  • EUR 920.00
  • EUR 443.00
  • EUR 220.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Horse Interleukin 8 (IL8). This antibody is labeled with HRP.

Interleukin 8 (IL8) Monoclonal Antibody (Horse), PE

4-MAA080Eq21-PE
  • EUR 325.00
  • EUR 3057.00
  • EUR 854.00
  • EUR 413.00
  • EUR 207.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Horse Interleukin 8 (IL8). This antibody is labeled with PE.

Interleukin 8 (IL8) Monoclonal Antibody (Chicken), APC

4-MAA080Ga22-APC
  • EUR 329.00
  • EUR 3041.00
  • EUR 854.00
  • EUR 416.00
  • EUR 212.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Chicken Interleukin 8 (IL8). This antibody is labeled with APC.

Interleukin 8 (IL8) Monoclonal Antibody (Chicken), Biotinylated

4-MAA080Ga22-Biotin
  • EUR 299.00
  • EUR 2288.00
  • EUR 684.00
  • EUR 363.00
  • EUR 214.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Chicken Interleukin 8 (IL8). This antibody is labeled with Biotin.

Interleukin 8 (IL8) Monoclonal Antibody (Chicken), Cy3

4-MAA080Ga22-Cy3
  • EUR 397.00
  • EUR 4013.00
  • EUR 1097.00
  • EUR 513.00
  • EUR 241.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Chicken Interleukin 8 (IL8). This antibody is labeled with Cy3.

Interleukin 8 (IL8) Monoclonal Antibody (Chicken), FITC

4-MAA080Ga22-FITC
  • EUR 283.00
  • EUR 2452.00
  • EUR 703.00
  • EUR 353.00
  • EUR 189.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Chicken Interleukin 8 (IL8). This antibody is labeled with FITC.

Interleukin 8 (IL8) Monoclonal Antibody (Chicken), HRP

4-MAA080Ga22-HRP
  • EUR 302.00
  • EUR 2652.00
  • EUR 756.00
  • EUR 377.00
  • EUR 200.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Chicken Interleukin 8 (IL8). This antibody is labeled with HRP.

Interleukin 8 (IL8) Monoclonal Antibody (Chicken), PE

4-MAA080Ga22-PE
  • EUR 283.00
  • EUR 2452.00
  • EUR 703.00
  • EUR 353.00
  • EUR 189.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Chicken Interleukin 8 (IL8). This antibody is labeled with PE.

Interleukin 8 (IL8) Monoclonal Antibody (Guinea pig)

4-MAA080Gu21
  • EUR 259.00
  • EUR 2708.00
  • EUR 670.00
  • EUR 328.00
  • EUR 219.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Guinea pig Interleukin 8 (IL8)

Interleukin 8 (IL8) Monoclonal Antibody (Guinea pig)

4-MAA080Gu24
  • EUR 259.00
  • EUR 2708.00
  • EUR 670.00
  • EUR 328.00
  • EUR 219.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Guinea pig Interleukin 8 (IL8)

Interleukin 8 (IL8) Monoclonal Antibody (Human), APC

4-MAA080Hu22-APC
  • EUR 307.00
  • EUR 2735.00
  • EUR 777.00
  • EUR 386.00
  • EUR 203.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Human Interleukin 8 (IL8). This antibody is labeled with APC.

Interleukin 8 (IL8) Monoclonal Antibody (Human), Biotinylated

4-MAA080Hu22-Biotin
  • EUR 283.00
  • EUR 2064.00
  • EUR 628.00
  • EUR 341.00
  • EUR 207.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Human Interleukin 8 (IL8). This antibody is labeled with Biotin.

Interleukin 8 (IL8) Monoclonal Antibody (Human), Cy3

4-MAA080Hu22-Cy3
  • EUR 368.00
  • EUR 3605.00
  • EUR 995.00
  • EUR 473.00
  • EUR 229.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Human Interleukin 8 (IL8). This antibody is labeled with Cy3.

Interleukin 8 (IL8) Monoclonal Antibody (Human), FITC

4-MAA080Hu22-FITC
  • EUR 266.00
  • EUR 2208.00
  • EUR 642.00
  • EUR 328.00
  • EUR 182.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Human Interleukin 8 (IL8). This antibody is labeled with FITC.

Interleukin 8 (IL8) Monoclonal Antibody (Human), HRP

4-MAA080Hu22-HRP
  • EUR 283.00
  • EUR 2387.00
  • EUR 690.00
  • EUR 351.00
  • EUR 192.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Human Interleukin 8 (IL8). This antibody is labeled with HRP.

Interleukin 8 (IL8) Monoclonal Antibody (Human), PE

4-MAA080Hu22-PE
  • EUR 266.00
  • EUR 2208.00
  • EUR 642.00
  • EUR 328.00
  • EUR 182.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Human Interleukin 8 (IL8). This antibody is labeled with PE.

Interleukin 8 (IL8) Monoclonal Antibody (Human), APC

4-MAA080Hu24-APC
  • EUR 307.00
  • EUR 2735.00
  • EUR 777.00
  • EUR 386.00
  • EUR 203.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Human Interleukin 8 (IL8). This antibody is labeled with APC.

Interleukin 8 (IL8) Monoclonal Antibody (Human), Biotinylated

4-MAA080Hu24-Biotin
  • EUR 283.00
  • EUR 2064.00
  • EUR 628.00
  • EUR 341.00
  • EUR 207.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Human Interleukin 8 (IL8). This antibody is labeled with Biotin.

Interleukin 8 (IL8) Monoclonal Antibody (Human), Cy3

4-MAA080Hu24-Cy3
  • EUR 368.00
  • EUR 3605.00
  • EUR 995.00
  • EUR 473.00
  • EUR 229.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Human Interleukin 8 (IL8). This antibody is labeled with Cy3.

Interleukin 8 (IL8) Monoclonal Antibody (Human), FITC

4-MAA080Hu24-FITC
  • EUR 266.00
  • EUR 2208.00
  • EUR 642.00
  • EUR 328.00
  • EUR 182.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Human Interleukin 8 (IL8). This antibody is labeled with FITC.

Interleukin 8 (IL8) Monoclonal Antibody (Human), HRP

4-MAA080Hu24-HRP
  • EUR 283.00
  • EUR 2387.00
  • EUR 690.00
  • EUR 351.00
  • EUR 192.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Human Interleukin 8 (IL8). This antibody is labeled with HRP.

Interleukin 8 (IL8) Monoclonal Antibody (Human), PE

4-MAA080Hu24-PE
  • EUR 266.00
  • EUR 2208.00
  • EUR 642.00
  • EUR 328.00
  • EUR 182.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Human Interleukin 8 (IL8). This antibody is labeled with PE.

Interleukin 8 (IL8) Monoclonal Antibody (Pig), APC

4-MAA080Po22-APC
  • EUR 349.00
  • EUR 3329.00
  • EUR 926.00
  • EUR 445.00
  • EUR 221.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Pig Interleukin 8 (IL8). This antibody is labeled with APC.

Interleukin 8 (IL8) Monoclonal Antibody (Pig), Biotinylated

4-MAA080Po22-Biotin
  • EUR 314.00
  • EUR 2499.00
  • EUR 737.00
  • EUR 384.00
  • EUR 220.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Pig Interleukin 8 (IL8). This antibody is labeled with Biotin.

Interleukin 8 (IL8) Monoclonal Antibody (Pig), Cy3

4-MAA080Po22-Cy3
  • EUR 423.00
  • EUR 4397.00
  • EUR 1193.00
  • EUR 552.00
  • EUR 253.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Pig Interleukin 8 (IL8). This antibody is labeled with Cy3.

Interleukin 8 (IL8) Monoclonal Antibody (Pig), FITC

4-MAA080Po22-FITC
  • EUR 299.00
  • EUR 2683.00
  • EUR 760.00
  • EUR 376.00
  • EUR 197.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Pig Interleukin 8 (IL8). This antibody is labeled with FITC.

Interleukin 8 (IL8) Monoclonal Antibody (Pig), HRP

4-MAA080Po22-HRP
  • EUR 319.00
  • EUR 2901.00
  • EUR 819.00
  • EUR 402.00
  • EUR 208.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Pig Interleukin 8 (IL8). This antibody is labeled with HRP.

Interleukin 8 (IL8) Monoclonal Antibody (Pig), PE

4-MAA080Po22-PE
  • EUR 299.00
  • EUR 2683.00
  • EUR 760.00
  • EUR 376.00
  • EUR 197.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Pig Interleukin 8 (IL8). This antibody is labeled with PE.

Interleukin 8 (IL8) Monoclonal Antibody (Pig), APC

4-MAA080Po24-APC
  • EUR 349.00
  • EUR 3329.00
  • EUR 926.00
  • EUR 445.00
  • EUR 221.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Pig Interleukin 8 (IL8). This antibody is labeled with APC.

Interleukin 8 (IL8) Monoclonal Antibody (Pig), Biotinylated

4-MAA080Po24-Biotin
  • EUR 314.00
  • EUR 2499.00
  • EUR 737.00
  • EUR 384.00
  • EUR 220.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Pig Interleukin 8 (IL8). This antibody is labeled with Biotin.

Interleukin 8 (IL8) Monoclonal Antibody (Pig), Cy3

4-MAA080Po24-Cy3
  • EUR 423.00
  • EUR 4397.00
  • EUR 1193.00
  • EUR 552.00
  • EUR 253.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Pig Interleukin 8 (IL8). This antibody is labeled with Cy3.

Interleukin 8 (IL8) Monoclonal Antibody (Pig), FITC

4-MAA080Po24-FITC
  • EUR 299.00
  • EUR 2683.00
  • EUR 760.00
  • EUR 376.00
  • EUR 197.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Pig Interleukin 8 (IL8). This antibody is labeled with FITC.

Interleukin 8 (IL8) Monoclonal Antibody (Pig), HRP

4-MAA080Po24-HRP
  • EUR 319.00
  • EUR 2901.00
  • EUR 819.00
  • EUR 402.00
  • EUR 208.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Pig Interleukin 8 (IL8). This antibody is labeled with HRP.

Interleukin 8 (IL8) Monoclonal Antibody (Pig), PE

4-MAA080Po24-PE
  • EUR 299.00
  • EUR 2683.00
  • EUR 760.00
  • EUR 376.00
  • EUR 197.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Pig Interleukin 8 (IL8). This antibody is labeled with PE.

Interleukin 8 (IL8) Monoclonal Antibody (Pig), APC

4-MAA080Po26-APC
  • EUR 349.00
  • EUR 3329.00
  • EUR 926.00
  • EUR 445.00
  • EUR 221.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Pig Interleukin 8 (IL8). This antibody is labeled with APC.

Interleukin 8 (IL8) Monoclonal Antibody (Pig), Biotinylated

4-MAA080Po26-Biotin
  • EUR 314.00
  • EUR 2499.00
  • EUR 737.00
  • EUR 384.00
  • EUR 220.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Pig Interleukin 8 (IL8). This antibody is labeled with Biotin.

Interleukin 8 (IL8) Monoclonal Antibody (Pig), Cy3

4-MAA080Po26-Cy3
  • EUR 423.00
  • EUR 4397.00
  • EUR 1193.00
  • EUR 552.00
  • EUR 253.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Pig Interleukin 8 (IL8). This antibody is labeled with Cy3.

Interleukin 8 (IL8) Monoclonal Antibody (Pig), FITC

4-MAA080Po26-FITC
  • EUR 299.00
  • EUR 2683.00
  • EUR 760.00
  • EUR 376.00
  • EUR 197.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Pig Interleukin 8 (IL8). This antibody is labeled with FITC.

Interleukin 8 (IL8) Monoclonal Antibody (Pig), HRP

4-MAA080Po26-HRP
  • EUR 319.00
  • EUR 2901.00
  • EUR 819.00
  • EUR 402.00
  • EUR 208.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Pig Interleukin 8 (IL8). This antibody is labeled with HRP.

Interleukin 8 (IL8) Monoclonal Antibody (Pig), PE

4-MAA080Po26-PE
  • EUR 299.00
  • EUR 2683.00
  • EUR 760.00
  • EUR 376.00
  • EUR 197.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Pig Interleukin 8 (IL8). This antibody is labeled with PE.

Interleukin 8 (IL8) Monoclonal Antibody (Rabbit), APC

4-MAA080Rb22-APC
  • EUR 352.00
  • EUR 3383.00
  • EUR 939.00
  • EUR 450.00
  • EUR 223.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Rabbit Interleukin 8 (IL8). This antibody is labeled with APC.

Interleukin 8 (IL8) Monoclonal Antibody (Rabbit), Biotinylated

4-MAA080Rb22-Biotin
  • EUR 316.00
  • EUR 2539.00
  • EUR 747.00
  • EUR 388.00
  • EUR 221.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Rabbit Interleukin 8 (IL8). This antibody is labeled with Biotin.

Interleukin 8 (IL8) Monoclonal Antibody (Rabbit), Cy3

4-MAA080Rb22-Cy3
  • EUR 428.00
  • EUR 4469.00
  • EUR 1211.00
  • EUR 559.00
  • EUR 255.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Rabbit Interleukin 8 (IL8). This antibody is labeled with Cy3.

Interleukin 8 (IL8) Monoclonal Antibody (Rabbit), FITC

4-MAA080Rb22-FITC
  • EUR 302.00
  • EUR 2726.00
  • EUR 771.00
  • EUR 380.00
  • EUR 198.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Rabbit Interleukin 8 (IL8). This antibody is labeled with FITC.

Interleukin 8 (IL8) Monoclonal Antibody (Rabbit), HRP

4-MAA080Rb22-HRP
  • EUR 322.00
  • EUR 2948.00
  • EUR 830.00
  • EUR 407.00
  • EUR 210.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Rabbit Interleukin 8 (IL8). This antibody is labeled with HRP.

Interleukin 8 (IL8) Monoclonal Antibody (Rabbit), PE

4-MAA080Rb22-PE
  • EUR 302.00
  • EUR 2726.00
  • EUR 771.00
  • EUR 380.00
  • EUR 198.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Rabbit Interleukin 8 (IL8). This antibody is labeled with PE.

Interleukin 8 (IL8) Monoclonal Antibody (Rhesus monkey)

4-MAA080Si21
  • EUR 259.00
  • EUR 2708.00
  • EUR 670.00
  • EUR 328.00
  • EUR 219.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Rhesus monkey Interleukin 8 (IL8)

Interleukin 8 (IL8) Monoclonal Antibody (Rhesus monkey)

4-MAA080Si22
  • EUR 259.00
  • EUR 2708.00
  • EUR 670.00
  • EUR 328.00
  • EUR 219.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Rhesus monkey Interleukin 8 (IL8)

Interleukin 8 (IL8) Monoclonal Antibody (Human, Dog), APC

4-MAA080Ca22-APC
  • EUR 307.00
  • EUR 2735.00
  • EUR 777.00
  • EUR 386.00
  • EUR 203.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Human, Dog Interleukin 8 (IL8). This antibody is labeled with APC.

Interleukin 8 (IL8) Monoclonal Antibody (Human, Dog), Biotinylated

4-MAA080Ca22-Biotin
  • EUR 283.00
  • EUR 2064.00
  • EUR 628.00
  • EUR 341.00
  • EUR 207.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Human, Dog Interleukin 8 (IL8). This antibody is labeled with Biotin.

Interleukin 8 (IL8) Monoclonal Antibody (Human, Dog), Cy3

4-MAA080Ca22-Cy3
  • EUR 368.00
  • EUR 3605.00
  • EUR 995.00
  • EUR 473.00
  • EUR 229.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Human, Dog Interleukin 8 (IL8). This antibody is labeled with Cy3.

Interleukin 8 (IL8) Monoclonal Antibody (Human, Dog), FITC

4-MAA080Ca22-FITC
  • EUR 266.00
  • EUR 2208.00
  • EUR 642.00
  • EUR 328.00
  • EUR 182.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Human, Dog Interleukin 8 (IL8). This antibody is labeled with FITC.

Interleukin 8 (IL8) Monoclonal Antibody (Human, Dog), HRP

4-MAA080Ca22-HRP
  • EUR 283.00
  • EUR 2387.00
  • EUR 690.00
  • EUR 351.00
  • EUR 192.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Human, Dog Interleukin 8 (IL8). This antibody is labeled with HRP.

Interleukin 8 (IL8) Monoclonal Antibody (Human, Dog), PE

4-MAA080Ca22-PE
  • EUR 266.00
  • EUR 2208.00
  • EUR 642.00
  • EUR 328.00
  • EUR 182.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Human, Dog Interleukin 8 (IL8). This antibody is labeled with PE.

Interleukin 8 (IL8) Monoclonal Antibody (Horse), APC-Cy7

4-MAA080Eq21-APC-Cy7
  • EUR 644.00
  • EUR 7474.00
  • EUR 1966.00
  • EUR 864.00
  • EUR 349.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Horse Interleukin 8 (IL8). This antibody is labeled with APC-Cy7.

Interleukin 8 (IL8) Monoclonal Antibody (Chicken), APC-Cy7

4-MAA080Ga22-APC-Cy7
  • EUR 538.00
  • EUR 5962.00
  • EUR 1588.00
  • EUR 713.00
  • EUR 304.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Chicken Interleukin 8 (IL8). This antibody is labeled with APC-Cy7.

MET un RON receptoru tirozīna kināzes kolorektālajā adenokarcinomā: molekulāras iespējas kā zāļu mērķi un antivielu un zāļu konjugāti ārstēšanai

Augstākā kolorektālā adenokarcinoma (CRAC), ko raksturo atšķirīgs histopatoloģisks izskats, tālu orgānu metastāzes, iegūta ķīmijrezistence un audzēja ģenētiskais stublājs, ir daudz neviendabīgu vēžu ar atšķirīgiem ģenētiskiem parakstiem un ļaundabīgiem fenotipiem. CRAC terapija onkologiem ir biedējoša darbība.

Šobrīd cīņā pret šo letālo slimību ir izmantotas daudzas metodes kopā ar molekulāro koncentrēšanos uz terapeitisko monoklonālo antivielu, mazmolekulāro kināzes inhibitoru un imūnregulācijas kontrolpunkta līdzekli. Tomēr šīs terapeitiskās metodes un pieejas gūst tikai ierobežotus panākumus. Tādējādi farmaceitiski vēlas atrast jaunus mērķus un izstrādāt jaunus CRAC līdzekļa terapijas līdzekļus. MET un RON receptoru tirozīna kināzes ir iesaistītas CRAC patoģenēzē.

Zinātniskie pētījumi ir atklājuši, ka novirzīta MET un / vai RON ekspresija un signalizācija ir būtiska, regulējot CRAC attīstību un ļaundabīgos fenotipus. Paaugstinātai MET un / vai RON izteiksmei ir arī CRAC attīstības un skartās personas izdzīvošanas prognozes vērtība.

Šīs iespējas piedāvā loģisko pamatu koncentrēties uz TER un RON zinātniskai CRAC iejaukšanai. Pašlaik, izmantojot mazmolekulārās kināzes inhibitorus, koncentrējoties uz MET CRAC terapijai, ir panākts būtisks progress, saņemot vairākus apstiprinājumus zinātniskai lietošanai.

Neskatoties uz to, uz antivielām balstītie bioterapeitiskie līdzekļi, lai arī zinātniski pētījumi veikti vairāk nekā astoņus gadus, ir guvuši nelielu progresu vai nav devuši nekādu progresu. Šajā novērtējumā mēs koncentrējamies uz MET un / vai RON nozīmi CRAC audzēja veidošanā un anti-MET, anti-RON un MET un RON-dual augšanu, koncentrējoties uz antivielu un zāļu konjugātiem zinātniskai lietderībai. Katra preklīniskā un zinātniskā pētījuma secinājumi agrāk vai vēlāk atklāj šī jaunā veida bioterapeitisko līdzekļu potenciālu CRAC ārstēšanai.

Seruma anti-Neu5Gc antivielu afinitātes attīrīšana atklāja paaugstinātu diapazonu un neobjektīvus masīvu repertuāra modeļus cilvēkiem, kuriem palielinājās Neu5Gc diapazons, bez antivielu afinitātes palielināšanās. Turklāt augsta gaļas svara samazināšanas plānā antivielu daudzveidības modeļi uz glikāna mikroelementiem mainījās ar Neu5Gcα3 saistīto glikānu virzienā, paaugstinot α3 / α6-glikānu attiecību.

Secinājumi: Mēs atklājām pārredzamu hipersaiti starp grādiem un seruma anti-Neu5Gc IgG un Neu5Gc patēriņu no rozā gaļas un piena produktiem. Šīs precīzās racionālās metodikas ļāva izstrādāt Gcemicindeksu, lai vienkāršotu Neu5Gc novērtēšanu ēdienreizēs, kas, bez šaubām, būtu pielāgots uztura ieteikumiem, lai samazinātu lielāko daļu vēža risku.

Antivielu reakcija uz suņu parvovīrusa vakcināciju suņiem ar hiperadrenokortikismu, kas tiek ārstēta ar Trilostane

  • Nav zināms, kā suņi ar hiperadrenokortikismu (HAC) reaģē uz vakcināciju. Šajā pētījumā tika izmērītas antivielas pretstatā suņu parvovīrusam (CPV) suņiem ar HAC, kas ar trilostānu apstrādāts agrāk un pēc CPV vakcinācijas, un atšķirībā no imūnās atbildes reakcijas uz veselīgu suņu reakciju. 
  • Vienpadsmit ilkņi ar HAC un pilnvērtīgi vecumam atbilstoši suņi (n = 31) ieguva modificētu dzīvo CPV vakcīnu. Antivielas ir izlemtas 0., 7. un 28. dienā ar hemaglutinācijas inhibīciju. Lai saskaņotu suņu imūnreakciju ar HAC un pilnvērtīgiem ilkņiem, tika izmantots vienveidīgais novērtējums.
  • Pirmsvakcinācijas antivielas (≥10) ir atklātas 100% suņu ar HAC (11/11; 95% TI: 70,0-100) un 93,5% pilnvērtīgu suņu (29/31; 95% TI: 78,3- 99.2). Suņiem ar HAC netika novērota ≥Four reizes lielāka antivielu titra palielināšanās, turpretī 22,6% pilnvērtīgu ilkņu gadījumā ≥Four reizes titra palielināšanās tika novērota (7/31; 95% TI: 11,1-40,1).
  • Maigi ar vakcīnu saistīti antagonistiski gadījumi (VAAE) ir konstatēti 54,5% suņu ar HAC (6/11; 95% TI: 28,0-78,8) un 29,0% pilnvērtīgu ilkņu (9/31; 95% TI: 15,9) -46,8). Nebija būtiskas atšķirības pirmsvakcinācijas antivielu klātbūtnē (p = 1.000), atbildes reakcija uz vakcināciju (p = 0.161), kā arī VAAE izplatības ziņā (p = 0.158). Imūnsistēmas suņu darbība ar HAC, kas apstrādāta ar trilostānu, šķiet līdzīga veselīgu ilkņu darbībai.

Linkeru izstrāde un validācija vietņu specifiskai antivielu-narkotiku konjugātu sagatavošanai, kas satur vairākas zāļu kopijas vienā cisteīna konjugācijas vietnē

Pirmās paaudzes cisteīna bāzes specifisko antivielu un zāļu konjugāti (ADC) ir ierobežoti līdz 1 narkotikai uz vienu cisteīnu. Neskatoties uz to, noteiktiem mērķiem nepieciešama pārmērīga zāļu un antivielu attiecība (DAR), kas atbilst zemas jaudas kravām. Palielinātu zāļu slodzi var panākt, izmantojot klasiskās cisteīna konjugācijas stratēģijas, tomēr tās noved pie neviendabīguma, neoptimālas efektivitātes un farmakokinētikas.

Šeit mēs aprakstām to heterobifunkcionālo saišu dizainu, sintēzi un apstiprināšanu, kuras var izmantot ADC ar divu, trīs un Four DAR sagatavošanai, katrai vietnei raksturīgā metodē vienā cisteīna konjugācijas vietnē, kas noved pie vietnei specifiskiem ADC ar DAR 4, seši un astoņi. Izstrādātie saites satur sulfhidrilam raksturīgu jodoacetilreaktīvu grupu un vairākas cikliskas diēna daļas, kas, izmantojot Dīla-Aldera reakciju, varētu efektīvi reaģēt ar lietderīgo slodzi ar maleimīdu nesošajām kravām.

 Kā idejas pierādījumu mēs sintezējām vietnei specifiskus DAR 4, sešus un astoņus ADC, kas satur tubulizīnu (AZ13601508), izmantojot inženierijas antivielas ar cisteīnu, kas ievietots aiz 239. vietas antivielu CH2 zonā.

Mēs novērtējām un atšķirībā no tā ADC in vitro citotoksicitāti, kas iegūta, izmantojot šeit aprakstīto vietnei specifisko platformu, ar ADC, kas gatavi izmantot klasisko cisteīna konjugāciju. Mūsu zināšanas apstiprināja jaunu konjugācijas platformu, kuras pamatā ir cisteīns, vietnei specifisku ADC sagatavošanai ar pārmērīgu zāļu slodzi terapeitiskos nolūkos.

 

Mouse Protectin (CD59) ELISA Kit

DLR-CD59-Mu-48T 48T
EUR 508
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Protectin (CD59) in samples from serum, plasma, urine or other biological fluids.

Mouse Protectin (CD59) ELISA Kit

DLR-CD59-Mu-96T 96T
EUR 661
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Protectin (CD59) in samples from serum, plasma, urine or other biological fluids.

Mouse Protectin (CD59) ELISA Kit

RDR-CD59-Mu-48Tests 48 Tests
EUR 534

Mouse Protectin (CD59) ELISA Kit

RDR-CD59-Mu-96Tests 96 Tests
EUR 742

Human Protectin (CD59) ELISA Kit

RD-CD59-Hu-48Tests 48 Tests
EUR 500

Human Protectin (CD59) ELISA Kit

RD-CD59-Hu-96Tests 96 Tests
EUR 692

Human Protectin (CD59) ELISA Kit

DLR-CD59-Hu-48T 48T
EUR 498
Description: A sandwich quantitative ELISA assay kit for detection of Human Protectin (CD59) in samples from serum, plasma, cell lysates or other biological fluids.

Human Protectin (CD59) ELISA Kit

DLR-CD59-Hu-96T 96T
EUR 647
Description: A sandwich quantitative ELISA assay kit for detection of Human Protectin (CD59) in samples from serum, plasma, cell lysates or other biological fluids.

Human Protectin (CD59) ELISA Kit

RDR-CD59-Hu-48Tests 48 Tests
EUR 522

Human Protectin (CD59) ELISA Kit

RDR-CD59-Hu-96Tests 96 Tests
EUR 724

Mouse Monoclonal Anti-Human CD59, (Biotin) (Clone 1F5) (mouse IgG1)

CD59-B 25 tests
EUR 408

Mouse Monoclonal Anti-Human CD59, (FITC) (Clone 1F5) (mouse IgG1)

CD59-F 25 tests
EUR 408

Mouse Monoclonal Anti-Human CD59, (PE) (Clone 1F5) (mouse IgG1)

CD59-PE 25 tests
EUR 408

Protectin (CD59) Monoclonal Antibody (Rabbit)

4-MAB336Rb21
  • EUR 251.00
  • EUR 2589.00
  • EUR 643.00
  • EUR 317.00
  • EUR 216.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Rabbit Protectin (CD59)

Protectin (CD59) Antibody

20-abx109633
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Protectin (CD59) Antibody

20-abx109634
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Protectin (CD59) Antibody

20-abx111491
  • EUR 732.00
  • EUR 398.00
  • 150 ul
  • 50 ul

Protectin (CD59) Antibody

20-abx323672
  • EUR 314.00
  • EUR 244.00
  • 100 ug
  • 50 ug

Protectin (CD59) Antibody

20-abx339758
  • EUR 411.00
  • EUR 300.00
  • 100 ul
  • 50 ul

Protectin (CD59) Antibody

20-abx001417
  • EUR 411.00
  • EUR 592.00
  • EUR 314.00
  • 100 ul
  • 200 ul
  • 50 ul

Protectin (CD59) Antibody

20-abx100397
  • EUR 411.00
  • EUR 133.00
  • EUR 1149.00
  • EUR 565.00
  • EUR 314.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Protectin (CD59) Antibody

20-abx100398
  • EUR 425.00
  • EUR 133.00
  • EUR 1177.00
  • EUR 578.00
  • EUR 328.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Protectin (CD59) Antibody

20-abx100399
  • EUR 439.00
  • EUR 133.00
  • EUR 1247.00
  • EUR 592.00
  • EUR 328.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Protectin (CD59) Antibody

20-abx100400
  • EUR 439.00
  • EUR 133.00
  • EUR 1247.00
  • EUR 592.00
  • EUR 328.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Protectin (CD59) Antibody

20-abx100401
  • EUR 467.00
  • EUR 133.00
  • EUR 1344.00
  • EUR 634.00
  • EUR 356.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Protectin (CD59) Antibody

20-abx100402
  • EUR 481.00
  • EUR 133.00
  • EUR 1442.00
  • EUR 676.00
  • EUR 356.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Protectin (CD59) Antibody

abx036096-100ug 100 ug
EUR 391

Protectin (CD59) Antibody

20-abx132385
  • EUR 328.00
  • EUR 843.00
  • EUR 439.00
  • EUR 154.00
  • EUR 258.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Protectin (CD59) Antibody

abx139305-01mg 0.1 mg
EUR 356

Protectin (CD59) Antibody

abx139307-01mg 0.1 mg
EUR 356

Protectin (CD59) Antibody

abx139306-01mg 0.1 mg
EUR 370

Protectin (CD59) Antibody

abx011952-100ug 100 ug
EUR 411

Protectin (CD59) Antibody

abx021467-100ug 100 ug
EUR 453

Protectin (CD59) Antibody

abx200391-100ug 100 ug
EUR 328

Protectin (CD59) Antibody

20-abx270064
  • EUR 467.00
  • EUR 537.00
  • EUR 272.00
  • EUR 815.00
  • EUR 356.00
  • 100 tests
  • 200 tests
  • 25 tests
  • 500 tests
  • 50 tests

Protectin (CD59) Antibody

20-abx210170
  • EUR 439.00
  • EUR 328.00
  • 100 ug
  • 50 ug

Protectin (CD59) Antibody

20-abx210424
  • EUR 411.00
  • EUR 300.00
  • 100 ul
  • 50 ul

Protectin (CD59) Antibody

20-abx178138
  • EUR 425.00
  • EUR 133.00
  • EUR 1177.00
  • EUR 578.00
  • EUR 328.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Protectin (CD59) Antibody

20-abx174238
  • EUR 815.00
  • EUR 425.00
  • 1 mg
  • 200 ug

Protectin (CD59) Antibody

20-abx225094
  • EUR 370.00
  • EUR 606.00
  • EUR 314.00
  • 100 ul
  • 200 ul
  • 50 ul

Protectin (CD59) Antibody

abx231489-100ug 100 ug
EUR 481

Anti-CD59 / Complement Regulatory Protein / Protectin Monoclonal Antibody

M00914 100ug/vial
EUR 397
Description: Mouse Monoclonal CD59 / Complement Regulatory Protein / Protectin Antibody. Validated in IF, IHC and tested in Human.

Protectin (CD59) Monoclonal Antibody (Rabbit), APC

4-MAB336Rb21-APC
  • EUR 352.00
  • EUR 3383.00
  • EUR 939.00
  • EUR 450.00
  • EUR 223.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Rabbit Protectin (CD59). This antibody is labeled with APC.

Protectin (CD59) Monoclonal Antibody (Rabbit), Biotinylated

4-MAB336Rb21-Biotin
  • EUR 316.00
  • EUR 2539.00
  • EUR 747.00
  • EUR 388.00
  • EUR 221.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Rabbit Protectin (CD59). This antibody is labeled with Biotin.

Protectin (CD59) Monoclonal Antibody (Rabbit), Cy3

4-MAB336Rb21-Cy3
  • EUR 428.00
  • EUR 4469.00
  • EUR 1211.00
  • EUR 559.00
  • EUR 255.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Rabbit Protectin (CD59). This antibody is labeled with Cy3.

Protectin (CD59) Monoclonal Antibody (Rabbit), FITC

4-MAB336Rb21-FITC
  • EUR 302.00
  • EUR 2726.00
  • EUR 771.00
  • EUR 380.00
  • EUR 198.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Rabbit Protectin (CD59). This antibody is labeled with FITC.

Protectin (CD59) Monoclonal Antibody (Rabbit), HRP

4-MAB336Rb21-HRP
  • EUR 322.00
  • EUR 2948.00
  • EUR 830.00
  • EUR 407.00
  • EUR 210.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Rabbit Protectin (CD59). This antibody is labeled with HRP.

Protectin (CD59) Monoclonal Antibody (Rabbit), PE

4-MAB336Rb21-PE
  • EUR 302.00
  • EUR 2726.00
  • EUR 771.00
  • EUR 380.00
  • EUR 198.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Rabbit Protectin (CD59). This antibody is labeled with PE.

Protectin (CD59) Polyclonal Antibody (Mouse)

4-PAB336Mu01
  • EUR 243.00
  • EUR 2457.00
  • EUR 613.00
  • EUR 305.00
  • EUR 212.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Protectin (CD59)

Mouse Protectin (CD59) Protein

20-abx068726
  • EUR 592.00
  • EUR 258.00
  • EUR 1776.00
  • EUR 704.00
  • EUR 439.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Protectin (CD59) Monoclonal Antibody (Rabbit), APC-Cy7

4-MAB336Rb21-APC-Cy7
  • EUR 585.00
  • EUR 6646.00
  • EUR 1759.00
  • EUR 781.00
  • EUR 326.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Rabbit Protectin (CD59). This antibody is labeled with APC-Cy7.

Protectin (CD59) Antibody (FITC)

20-abx106664
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Protectin (CD59) Antibody (FITC)

20-abx106665
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Protectin (CD59) Antibody (HRP)

20-abx108081
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Protectin (CD59) Antibody (HRP)

20-abx108082
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Protectin (CD59) Antibody (Biotin)

20-abx105246
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Protectin (CD59) Antibody (Biotin)

20-abx105247
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Protectin (CD59) Antibody (FITC)

abx134463-100Assays 100 Assays
EUR 439

Protectin (CD59) Antibody (FITC)

abx134463-50Assays 50 Assays
EUR 342

Protectin (CD59) Antibody (APC)

abx139309-100tests 100 tests
EUR 481

Protectin (CD59) Antibody (Biotin)

abx139310-01mg 0.1 mg
EUR 425

Protectin (CD59) Antibody (FITC)

abx139311-100tests 100 tests
EUR 425

Protectin (CD59) Antibody (PE)

abx139308-100tests 100 tests
EUR 481

Protectin (CD59) Antibody (RPE)

abx412706-100tests